16 articles for “Curcumin”

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Research ArticleOpen accessEvery word in the titleAntitumor and Quantitative Structure Activity Relationship Study for Dihydropyridones Derived from CurcuminBahjat A. Saeed, Kawkab Y. Saour, Rita S. Elias et al.Problem statement: Pyridones are known to have variety of biological activities like antitumor, antibacterial, antiinflamatory and antimalarial activities. This study presented antitumor evaluation of dihydropyridones derived from curcumin, as well as curcumin for comparison. Approach: The compounds evaluated for a preliminary estimation of the in vitro tumor inhibiting activity against 11 of tumor cell lines by using Microculture Tetrazolium assay … …American Journal of Immunology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,262 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleDevelopment of Curcumin Based Ophthalmic FormulationD. Anjana, K. Anitha Nair, N. Somashekara et al.Problem statement: Ophthalmic drug delivery system has been a major challenge due to the distinctive and unique anatomy of the eye. The use of phytochemicals for the application in ocular disease has not been investigated much, due to poor pharmacokinetics of phytochemical and hence poor therapeutic efficacy. Approach: Curcumin is one such phytochemical known for its medicinal properties, but its … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Feb 2012 · 15,401 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Investigation of 1H NMR Spectra of 2,3-Dihydro-4-Pyridinones Derived from BisdemethoxycurcuminWisam A. Radhi, Bahjat A. SaeedProblem statement: The studied dihydropyridones were synthesized via microwave assisted reaction of bisdemethoxycurcumin and amines or amine acetates which is new approach in the synthesis of this important class of compounds and the deep study of their NMR spectra seems reasonable. Approach: 1H NMR spectra of dihydropyridones derived from curcumin were discussed and their structures were elucidated accordingly. Results: The … …American Journal of Applied Sciences, Vol. 7, Issue 8 · 31 Aug 2010 · 7,186 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCrystal Structure of 2-(4-Hydroxy-3-Methoxyphenyl)-6- (4-Hydroxy-3-Methoxystyryl)-1-Methyl-2, 3-Dihydropyridine-4 (1H)-One by X-Ray Powder DiffractionBahjat A. Saeed, Kawkab Y. Saour, Rita S. Elias, Deng XiaodiProblem statement: The studied dihydropyridone was synthesized for the first time via the microwave assisted reaction of curcumin and methylamine and it is important to support the mechanism by the crystal structure. Approach: The crystal structure of the title compound was determined using high resolution x-ray diffraction. PowderSolve program was used to solve the structure while the refinement was done … …American Journal of Applied Sciences, Vol. 7, Issue 7 · 31 Jul 2010 · 7,160 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBoric Acid Levels in Fresh Noodles and Fish BallPang-Hung Yiu, Jian See, Amartalingam Rajan, Choon-Fah J. BongBoric acid (H3BO3) is detrimental to human health if consumed in excess. However, it continues to be used in the production of food especially noodles and some processed seafood such as fish ball. Five kinds of noodles and a type of fish ball were collected over a period of four weeks from a random sample of manufacturers in Bintulu, Sarawak, … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 2 · 30 Jun 2008 · 10,609 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDengue Virus Infection Induced NF-κB-dependent Macrophage Migration Inhibitory Factor ProductionLien-Cheng Chen, Huey-Wen Shyu, Huan-Yao Lei et al.Dengue virus (DV) infection can cause mild dengue fever or severe dengue hemorrhage fever and dengue shock syndrome. Macrophage migration inhibitory factor (MIF) is a cytokine that plays an important role in the modulation of inflammatory and immune responses and serum levels of MIF are correlated with disease severity in dengue patients. However, the mechanism that induces MIF production during … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,290 accessesView PDF Cite