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19 results for “Computational biology”

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Research ArticleOpen accessIn the abstractComputing MDR-Game with Applications to Real DataJimbo Henri Claver, Takeru Suzuki, Jesus Pascal et al.Originally developed for probability and statistic purposes, Multiple Dice Rolling (MDR) game turns out to be useful for many other applications such as complex biological systems and medical research. It has been mainly used to estimate system states that cannot be observed directly. MDR game is affected by noise and fluctuations. It is widely agreed that noise in dynamic systems … …Journal of Computer Science, Vol. 14, Issue 7 · 17 Jul 2018 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproving Protein 3D Structure Prediction Accuracy using Dense Regions Areas of Secondary Structures in the Contact MapAmer F. Al-Badarneh, Mohammad A. Khalil, Mo'taz A. Al-HamiProblem Statement: The protein folding problem is a fundamental problem in structural molecular biology. This problem describes how a protein is transformed from its primary sequence (i.e., amino acid sequence) into the three dimensional structure (3D structure) for this sequence that determines the function of the protein. The 3D structure of a protein can be represented using a square symmetrical … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Survey of Protein Fold Recognition AlgorithmsMohammed Said Abual-Rub, Rosni AbdullahProblem statement: Predicting the tertiary structure of proteins from their linear sequence is really a big challenge in biology. This challenge is related to the fact that the traditional computational methods are not powerful enough to search for the correct structure in the huge conformational space. This inadequate capability of the computational methods, however, is a major obstacle in facing … …Journal of Computer Science, Vol. 4, Issue 9 · 30 Sep 2008 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Algorithm Based Probabilistic Motif Discovery in Unaligned Biological SequencesM. Hemalatha, K. VivekanandanFinding motif in biosequences is the most important primitive operation in computational biology. There are many computational requirements for a motif discovery algorithm such as computer memory space requirement and computational complexity. To overcome the complexity of motif discovery, we propose an alternative solution integrating genetic algorithm and Fuzzy Art machine learning approaches for eliminating multiple sequence alignment process. Problem … …Journal of Computer Science, Vol. 4, Issue 8 · 31 Aug 2008 · 6,729 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractEncouraging High School Student Interest in Computing Studies in GCC: UAE Case StudyManar Abu TalibComputational studies have an impact on fields like biology, chemistry, linguistics, psychology, economics and statistics. They develop skills such as problem solving and systems design and improve understanding about the power and limits of human and machine intelligence. The Global Science Forum emphasizes on collecting accurate and unbiased information as important strategy to increase the attractiveness of Science and Technology … …Journal of Computer Science, Vol. 11, Issue 11 · 11 Jan 2016 · 6,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractParallel Algorithms for String Matching Problem on Single and Two Dimensional Reconfigurable Pipelined Bus SystemsS. Viswanadha Raju, A. Vinaya BabuWe considered string matching on LARPBS and 2D LARPBS. This has applications such as string databases, cellular automata and computational biology. The main use of this method is to reduce the time spent on comparisons in string matching by using LARPBS. We investigated exact string matching and approximate string matching problems. For these two sub problems, we obtained O (n) … …Journal of Computer Science, Vol. 3, Issue 9 · 30 Sep 2007 · 6,530 accessesView PDFCite