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32 articles for “Combination Therapy”
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Research ArticleOpen accessIn the abstractThe Association of HLA Class II Alleles with the Response to Alfa-Interferon/Ribavirin Therapy in Chronic Hepatitis C PatientsAwny Aly Abol-Ez Gawish, Nahla Abd El-Hamid Mohammed, Rasha Adel Sayed Ahmed Hussein, Elsaid Galal El-BadrawyHuman Leucocyte Antigens (HLA) class II appears to play an important role in the individual’s immune response to viral infection. The present study was aimed at assessment of the relationship between HLA DRB1 alleles and the response to HCV combined therapy in Chronic Hepatitis C patients (CHC). We enrolled a total of 44 chronically infected HCV patients without Hepatitis B … …American Journal of Immunology, Vol. 11, Issue 3 · 12 Nov 2015 · 6,700 accessesView PDFCite
Review ArticleOpen accessIn the abstractDiagnosis of Pain in Small Companion AnimalsGiorgia della Rocca, Alice Catanzaro, Alessandra Di Salvo, Mary Ellen GoldbergIt is now widely accepted that animals are able to experience pain in a similar way to humans. Acute and/or chronic pain is associated not only with many surgical procedures, but also with various medical diseases, where pain may increase morbidity and mortality. Moreover, some types of pain (e.g., neuropathic pain) can be considered as an illness in themselves. Recognizing … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 15 Jun 2015 · 7,997 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 GuidelinesKrishna Murti, M. Arif Khan, Akalanka Dey et al.The main objective of the present study to investigate the utilization pattern of antihypertensive drugs in hypertensive patients and to find out whether the prescription pattern is in adherence with the JNC7 guidelines for the management of hypertension. A prospective study was conducted and drug utilization data were collected from 137 hypertensive patients who were attended as Out Patient Department … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 2 Jun 2015 · 8,273 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Usage in Intensive Care Units of Tabriz Imam Reza Hospital, 2011Sepehr Taghizadeh, Mehdi Haghdoost, Omid Mashrabi, Zahra ZeynalikhasraghiDrug therapy is one of the most important factors in providing community health. In a proper selection of an antibiotic for curing an infection, the kind of infective agent and its sensitivity to the utilized drugs must be regarded. The patients whom are admitted in ICUs are 5 to 7 folds more vulnerable to infection. The studies has been done … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 22 Nov 2013 · 7,715 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of IL-10 in Urinary Bladder Carcinoma and Bacillus Calmette-Guerin ImmunotherapyYi Luo, Eric J. Askeland, Mark R. Newton, Michael A. O’DonnellProblem statement: Bladder cancer is a common urologic cancer and intravesical Mycobacterium bovis Bacillus Calmette-Guerin (BCG) is the mainstay in the treatment of superficial bladder cancer. However, the current BCG therapy is not desirable with respect to its efficacy and side effects. Interleukin (IL)-10, a T helper type (Th) 2 cytokine, plays an important regulatory role in bladder cancer immunosurveillance … …American Journal of Immunology, Vol. 8, Issue 1 · 9 Mar 2012 · 8,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Antioxidant Vitamins C and E Supplementation on its Plasma Levels and on Lipid Profile in Pulmonary Tuberculosis PatientsM. Madhavi, P. Samudram, A. Hemanth Kumar, Lalitha VictorProblem statement: Patients with active pulmonary Tuberculosis (TB) are malnourished as indicated by reductions in lean mass, anthropometric indices and micronutrient status. Supplementation with vitamins may prove to be beneficial. Limited information is available on the supplementation of vitamin C and E in pulmonary TB patients. Hence, the present study was undertaken to address the question whether any benefit could … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,684 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Clonal Clusters of Klebsiella pneumoniae Isolates from Chennai by Extended Spectrum Beta Lactamase Genotyping and Antibiotic Resistance Phenotyping AnalysisC. Kamatchi, H. Magesh, Uma Sekhar, Rama VaidyanathanProblem statement: An increased resistance to antibiotics has been reported in Klebsiella pneumoniae, an opportunistic gram negative pathogen belonging to Entrobacteraceae due to the evolution and spread of plasmid encoded extended spectrum beta lactamases and other genes conferring cross-resistance to other antibiotics. This is of concern due to the increasing cost of antibiotic treatment and the spread of multidrug resistance … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,953 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Antidiabetic Efficacy of Combined Extracts from Two Continental Plants: Azadirachta indica (A. Juss) (Neem) and Vernonia amygdalina (Del.) (African Bitter Leaf)Patrick Ekong Ebong, Item Justin Atangwho, Eyong Ubana Eyong, Godwin Eneji EgbungPolyherbal therapy is said to be a current pharmacological principle having the advantage of producing maximum therapeutic efficacy with minimum side effects. We assessed the antidiabetic efficacy and hence the impact on biochemical indices of toxicity by a combination of extracts from neem and bitterleaf. Thirty rats, 25 diabetic and 5 non-diabetic rats, were used for the study. The diabetic … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 31 Aug 2008 · 14,400 accessesView PDFCite
Research ArticleOpen accessIn the abstractStandard Versus Specific Therapy for Chronic Osteomyelitis TreatmentAngela Ingianni, Giorgio Lampis, Samuela Laconi et al.58 patients with chronic osteomyelitis were treated either with a standard therapy or with a specific targeted therapy based on the antibiogram assay. Standard therapy was performed by a 15-day course of a parenteral cephalosporin (usually ceftriaxone) in combination with an aminoglycoside (e.g. netilmicin), followed by oral therapy with a fluoroquinolone (generally ciprofloxacin) for 1 to 3 months; specific therapy … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractTissue Engineering of Articular Cartilage: A Mini-ReviewRadoslav Zamborsky, Jana Rusnakova, Andreas NicodemouDamage of articular cartilage due to congenital anomaly, injury or pathological process may lead in decreasing of life quality of affected patients. In many cases, conventional therapeutical approaches may not bring expected results. Tissue engineering by the combination of material technology and cell-based therapy may represent hope for these patients. The main goal of this review article is to summarize … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 5 Jan 2015 · 6,925 accessesView PDFCite