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25 articles for “Cognitive Impairment”
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Research ArticleOpen accessIn the abstractMulberry Fruits Extract Mitigate Vascular DementiaPratchaya Kaewkaen, Jintanaporn Wattanathorn, Terdthai Thong-Un et al.To date, Vascular Dementia (VaD) is the second most commonly found dementia following Alzheimer�s disease. Though VaD is still increasing its importance, the therapeutic efficacy is still not in satisfaction level. Therefore, the searching for an acceptable cheap and safe neuroprotective agent is in a great demand. Based on the neuroprotective and cognitive enhancing effects in alcohol neurotoxicity of mulberry … …American Journal of Applied Sciences, Vol. 9, Issue 11 · 1 Sep 2012 · 6,967 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Cognitive Enhancing Effect of Tomato PomaceWipawee Thukhammee, Jintanaporn Wattanathorn, Supaporn Muchimapura et al.Poor learning abilities and impaired memory are increasing their importance in accompany with the increased elderly population and stress exposure. Therefore, the development of cognitive enhancement is required. Recent findings showed that oxidative stress played the important role on the development of cognitive impairment in various conditions. Therefore the development of cognitive enhancer from vegetable possessing antioxidant is focused. The … …American Journal of Applied Sciences, Vol. 9, Issue 11 · 31 Aug 2012 · 7,022 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Mulberry Fruit Powder in Animal Model of StrokePratchaya Kaewkaen, Terdthai Tong-Un, Jintanaporn Wattanathorn et al.Stroke is the leading cause of death and the important cause of disability worldwide. Presently, the effectiveness of therapeutic strategy is still very limited. Based on the role neuroprotective effect of substance possessing antioxidant effect previously reported, we hypothesized mulberry fruit a substance possessing anti-oxidant activity, might be able to protect against cognitive impairment induced by stroke or cerebral ischemia. … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 15 Aug 2012 · 9,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Protects Against Age-Related Cognitive DeclineJintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukhammee et al.Problem statement: The phenolic compounds and anthocyanin contents, the antioxidant and Acetylcholinesterase Inhibitor (AChI) activities of mulberry fruits were determined. Approach: Analysis of phenolic compounds and anthocyanin were performed using Folin Ciocalteu reagent and pH-differential method respectively. The antioxidant activity was determined using DPPH and FRAP assays while AChI activity was determined using Ellman method. Results: The mulberry fruit powder … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 8 Aug 2012 · 7,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Alzheimer's Disease of Porcine Brain ExtractWipawee Thukham-Mee, Jintanaporn Wattanathorn, Supaporn Muchimapura, Chuleratana BunchonglikitkulProblem statement: Despite the increasing importance of Alzheimer’s disease, no effective therapeutic strategy is available. Therefore, neuroprotective strategy is still required. Recent findings show that numerous substances possessing antioxidant can improve neurodegeneration and memory impairment. Based on the antioxidant effect and its reputation to serve as brain tonic in traditional folklore, we hypothesized that porcine brain extract could mitigate neurodegeneration … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 8,243 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruit Mitigates Alcohol Neurotoxicity and Memory Impairment Induced by Chronic Alcohol IntakeJintanaporn Wattanathorn, Nattaporn Phunchago, Supaporn Muchimapura et al.Problem statement: To date, the therapeutic strategy efficacy against memory impairment induced by alcohol intoxication is still limited. The novel therapeutic strategy which is easy to approach, less toxic and less cost is required. Based on the role of oxidative stress in memory impairment induced by alcohol, the neuroprotective effect of substance possessing antioxidant has gained much attention. Therefore, we … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 8 Feb 2012 · 9,328 accessesView PDFCite
Research ArticleOpen accessIn the abstractDementia in Parkinson's Disease: A Clinical ReviewRenata Teles Vieira, Leonardo Caixeta, Sergio Machado, Marcelo CaixetaProblem statement: Idiopathic Parkinson's Disease (PD) has being increasingly seen as a neuropsychiatric entity and no longer purely neurological, given the frequency and exuberance with which the psychiatric manifestations occurs. Approach: This review will focus on the epidemiology, clinical aspects, differential diagnosis with Alzheimer's Disease (AD) associated with parkinsonism, Dementia with Lewy Bodies (LBD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration … …Neuroscience International, Vol. 2, Issue 1 · 23 Nov 2011 · 7,764 accessesView PDFCite
Research ArticleOpen accessIn the abstractGinger Supplementation Enhances Working Memory of the Post-Menopause WomenNaritsara Saenghong, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: Cognitive impairment is one important problem in post-menopausal women. Although hormone therapy can improve this condition, it also produces adverse effect. Recent findings showed that this condition could be mitigated by the herb. Ginger or Zingiber officinale Roscoe, a plant in a family of Zingiberaceae, was previously demonstrated the neuroprotection and cognitive enhancing effects. Therefore, this study was … …American Journal of Applied Sciences, Vol. 8, Issue 12 · 10 Oct 2011 · 10,065 accessesView PDFCite
Research ArticleOpen accessIn the abstractCognitive-Enhancing and Antioxidant Activities of Quercetin Liposomes in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of Alzheimer’s Disease (AD). Antioxidant intake is beneficial to delay or inhibit the progression of this disease. Quercetin, a bioflavonoid in fruits and vegetables, has a powerful antioxidant activity both in vitro and in vivo. Claims that quercetin has many biological activities. However, quercetin is rapidly … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 31 Oct 2010 · 7,880 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Mitochondrial Dysfunction in Autism and Implications for TreatmentDaniel A. Rossignol, J. Jeffrey BradstreetClassical mitochondrial diseases occur in a subset of individuals with autism and are usually caused by genetic anomalies or mitochondrial respiratory pathway deficits. However, in many cases of autism, there is evidence of mitochondrial dysfunction (MtD) without the classic features associated with mitochondrial disease. MtD appears to be more common in autism and presents with less severe signs and symptoms. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 16,373 accessesView PDFCite