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19 results for “Clearly Demonstrated”
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Research ArticleOpen accessIn the abstractIn Silico and in Vitro Studies: Tryparedoxin Peroxidase Inhibitor Activity of Methotrexate for Antileishmanial ActivityRavi Kumar Gundampati, Shraddha Sahu, Avinash Kumar Srivastava et al.In order to understand the mechanism of molecular interactions at the active site of Tryparedoxin Peroxidase (Try P), homology modeling and docking studies were performed. We generated a Three-Dimensional (3D) model of target protein based on the Crystal structure of Leishmania Major Try PI (PDB ID: 3TUE) using modeler software. Docking analysis was carried out to study the effects of … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 28 Nov 2013 · 7,893 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntidepressant-Like Effects of Selected Crude Extracts of Pilea microphylla in Mice Model of DepressionAmir Modaressi Chahardehi, Darah Ibrahim, Fabrid Aboulhasani, Shaida Fariza SulaimanThe present study was undertaken to investigate the effect of selected crude extracts namely, Methanol (ME I), Chloroform Extract (CE II) and Ethyl Acetate (EAE II) extracts of Pilea microphylla on depression in mice. In the present study, the antidepressant effect of P. microphylla was examined due to its rich flavonoid contents in the Urticaceae family using two behavioral models, … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 19 Mar 2013 · 7,942 accessesView PDFCite
Research ArticleOpen accessIn the abstractEcological Monitoring of Danube water Quality in Budapest RegionHosam E.A.F. Bayoumi Hamuda, Istvan PatkoProblem statement: Serious health problems and other economic costs related to water treatment, remediation and locating a new water supply, become an evidence of water pollution caused by human activities. The main problems of the Danube River basin are associated with nutrients, organic pollution and hazardous pollutants. The aim of the study is to assess the surface water of the … …American Journal of Environmental Sciences, Vol. 8, Issue 3 · 5 Apr 2012 · 9,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Learning Styles on Learning Strategy Use by EFL LearnersWeng Pei-ShiProblem statement: Strategies play a significant role in assisting learners with developing language competence. During the past few years, numbers of studies demonstrated the importance of learning strategies in language learning. Approach: Positive relationship between strategy use and reading comprehension was presented and the differences of strategy use between successful and less successful learners were highly discussed in much research. … …Journal of Social Sciences, Vol. 8, Issue 2 · 29 Feb 2012 · 9,733 accessesView PDFCite
Research ArticleOpen accessIn the abstractTurning Risks into Opportunities in Contract Management: A Case Study in the Health Care IndustryElizabeth McVickerProblem statement: This case study presented students with a situation based in the healthcare industry, highlighting the importance of contract review, clear communications and interestbased negotiations in order to avoid the costly consequences that could be associated with contract related disputes. The case allowed students to understand how clearly written contracts play a deciding role in the success of business … …American Journal of Economics and Business Administration, Vol. 3, Issue 2 · 7 Apr 2011 · 7,344 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuercetin, Quercetrin Except Rutin Potentially Increased Pirarubicin Cytotoxicity by Non-Competitively Inhibiting the P-Glycoprotein-and MRP1 Function in Living K562/adr and GLC4/adr CellsWinit Choiprasert, Nathupakorn Dechsupa, Suchart Kothan et al.Problem statement: Quercetin and its glycoside derivatives are increasingly receiving interests as new generation of anticancer molecules and were recognized by multidrug resistant transporters such as P-glycoprotein and MRP1 protein. Of relevance to their use as anticancer agents alone or in combination with other agents, this study aims to analyze the interaction of the compounds with the MDR transporters including … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 9,670 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Novel Chromosomal Abnormalities, inv(5)(p13q13) and t(7;18)(q32;q21), Associated with AutismZheng Chen, Xiao-bing Zou, Ya-nan Zhang et al.Autism is a neurodevelopmental disorder defined by impairments in social interaction, communication, as well as restricted and stereotyped behaviors. While the etiology of autism remains largely unknown, the existence of genetic components has been clearly demonstrated in autistic pathogenesis. The incidence of autism is 50-100 fold greater in the population with autistic family history than the general population. Chromosomal abnormalities … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 6,773 accessesView PDFCite
Research ArticleOpen accessIn the abstractAutonomic Middleware Services for Just-In-Time Grid Services ProvisioningWail M. Omar, A. Taleb-Bendiab, Yasir KaramThe advent of widespread distributed computing environment, such as information systems and computational grids computing has enabled a new generation of applications that are based on seamless access, aggregation and interaction. The dramatic side of the story is a strong presence of the plea that those decentralized Grids are potentially affected by a number of primitives derived from their anatomy, … …Journal of Computer Science, Vol. 2, Issue 6 · 30 Jun 2006 · 6,579 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Changing Pathology of NeuroAIDS Associated with Drug Abuse in the Era of HAARTE Bell Jeanne, C. Anthony Iain, Simmonds PeterCompliance with highly active antiretroviral therapy (HAART) arrests HIV induced immune collapse and reduces the prevalence of severe central nervous system (CNS) complications, including HIV associated dementia and encephalitis. However minor cognitive disorders remain common and recent autopsy studies have demonstrated the presence of subtle neuropathological abnormalities in HAART treated individuals, including persistent neuroinflammation and enhanced deposition in the brain … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,872 accessesView PDFCite