Research ArticleOpen accessIn the abstractTelomere Length and Gut Microbiota: Integrating Advanced Glycation End Products (Ages) With Artificial Intelligence for Understanding Premature AgingDiniwati Mukhtar, Hanifah HafsariPremature aging is characterized by an accelerated decline in biological functions, increasing the risk of chronic diseases. This review explores the interconnected roles of three critical biomarkers: Telomere Length, gut microbiota composition, and Advanced Glycation End Products (AGEs). These biomarkers exhibit bidirectional relationships, influencing one another and contributing to the aging process. Understanding their interplay provides valuable insights into the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 3 Sep 2025 · 5,623 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpidemiological Insights and Case Fatality Analysis of SARS-CoV-2 in Indian States During the First WaveRakesh Kaushik, Nikita et al.Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has globally spread, causing a significant health crisis. India, with over 157,000 fatalities, ranks third globally in mortality cases. While vaccine development has played a pivotal role in decelerating the virus's spread, understanding the specific factors influencing morbidity and mortality during the first wave remains essential. This retrospective study analyzes data from 28 Indian … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 21 Jan 2025 · 4,312 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,825 accessesView PDFCite
Research ArticleOpen accessIn the abstractMycobacterium Chimaera. A Lethal Enemy of Cardiac SurgeryAnna Llorens Ferrer, Elisabet Berastegui Garcia, Lourdes Mateu Pruñosa, Christian Muñoz GuijosaMycobacterium chimaera (M. chimaera) can cause disseminated infection and Infective Endocarditis (IE) in patients with previous cardiac surgery. M. chimaera is acquired during cardiopulmonary bypass via bioaerosols emitted from contaminated heater-cooler units water systems. M. chimaera infections can cause pneumonia, especially in patients with underlying chronic pulmonary diseases like cystic fibrosis and Chronic Obstructive Pulmonary Disease (COPD), cardiovascular manifestations and … …American Journal of Infectious Diseases, Vol. 17, Issue 2 · 1 Jun 2021 · 7,310 accessesView PDFCite
EditorialOpen accessIn the abstractMechanisms and Management of Chronic PainVictor V. ChabanChronic pain symptoms account up to half of all health care visits, afflicts >10% of US adults, at a higher prevalence in women with current analgesic drugs rarely provide enough efficacy in the absence of serious side effects. Chronic pain is also the root cause of the national opioid health crisis, which adds to health care costs and deaths. Thus, … …International Journal of Research in Nursing, Vol. 12, Issue 1 · 14 Jan 2021 · 7,205 accessesView PDFCite
Case ReportOpen accessIn the abstractLessons Learned: Barriers to Hemoglobin A1c Monitoring in Rural Northern TanzaniaAndrea Fortson Knopp, Erika Metzler SawinIn sub-Saharan countries, Non-communicable Chronic Diseases (NCDs), including diabetes, are on the rise. Glycated hemoglobin (HbA1c) is a Point Of Care (POC) diagnostic tool for diabetic monitoring that is unavailable in many resource-constrained environments worldwide. Theoretically, HbA1c measurement is practical in these settings because fasting is not required, the test is not generally repeated before 120 days and travel time … …International Journal of Research in Nursing, Vol. 11, Issue 1 · 8 Jan 2021 · 6,231 accessesView PDFCite
Review ArticleOpen accessIn the abstractArtificial Intelligence in COVID-19 Management: A Systematic ReviewSamaneh Mohammadi, SeyedAhmad SeyedAlinaghi et al.With the development of modern technologies in the field of healthcare, the use of Artificial Intelligence (AI) in disease management is increasing. AI methods may assist healthcare providers in the COVID-19 era. The current study aimed to observe the efficacy and importance of AI for managing the COVID-19 pandemic. An organized search was conducted, utilizing PubMed, Web of Science, Scopus, … …Journal of Computer Science, Vol. 19, Issue 5 · 30 Mar 2023 · 8,062 accessesView PDFCite
Research ArticleOpen accessIn the abstractOrlistat Induce Renal Toxicity, DNA Damage, and Apoptosis in Normal and Obese Female RatsHaneen Mushtaq Hameed, Ahmed Flayyih Hasan, Zainab Haytham Razooki et al.Obesity has been linked to several chronic diseases, including fatty liver disease, fatty heart disease, diabetes mellitus, hypertension, obstructive sleep apnea, and cancer. The purpose of the current study was to determine how Orlistat affected renal toxicity, DNA damage, and apoptosis that were brought on by obesity in normal and obese female rats. There were four groups made up of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 18 Jan 2023 · 5,836 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Markers of Insulin Resistance in Feline Hypertrophied Myocardium. Insulin Resistance in Heart FailureOleinikov Dmitrii ArkadievichInvestigation of myocardial tissue concentration of ATP, glucose transporters 1 and 4, pyruvate dehydrogenase, hexokinase 2, insulin receptor and adropin proteins, determining metabolic changes and possible insulin resistance in feline myocardium with hypertrophic phenotype. This is the pilot study for metabolic markers determination. Eighteen cats were studied, divided into 3 groups: Without cardiac disease (n = 5), cats with hypertrophic … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 4 · 13 Nov 2020 · 6,332 accessesView PDFCite
Review ArticleOpen accessIn the abstractBioactive Functional Foods for Cardiovascular DiseasesKiren Mustafa, Iqra Ajmal, Tahira Naz et al.Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 17 Aug 2020 · 7,842 accessesView PDFCite