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18 results for “Chemical Drugs”
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Research ArticleOpen accessIn the abstractLeptospirosis in the Tropics: When Prevention Doesn't Easily Sell as a Ton of CureRoger Lee MendozaProblem statement: Human leptospirosis -- the most widespread zoonotic disease -- thrives in tropical and subtropical climates. It is seldom addressed ex ante or prior to an outbreak or expected outbreak by governments of high-risk countries. Whether common, post-exposure treatment with antimicrobial drugs is more cost-efficient than reducing animal reservoir populations was the overarching question that guided this study. A … …American Journal of Economics and Business Administration, Vol. 2, Issue 3 · 30 Sep 2010 · 8,381 accessesView PDFCite
Research ArticleOpen accessIn the abstractStandardization of Metal-Based Herbal MedicinesArun Sudha, V. S. Murty, T. S. ChandraProblem statement: Standardization of herbal drugs is a burning topic in herbal drug industry today. Standardization is difficult because they are usually mixtures of many constituents and the active principle in most cases is unknown. However it is possible to generate a physico-chemical fingerprint for the standardization of these drugs with reference to authentic drugs, for monitoring variation between preparations … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,906 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy of Closantel 5% against Cattle Gastrointestinal ParasitesY. Garedaghi, A.P. Rezaii Saber, R. AttaremadrakiProblem statement: There are several anthelmintic classes based on chemical structure that are in use, but, during the last 20 years, it has been increasingly noted that the target parasites have become resistant, the incidence varying with geographical location and mode of use. Approach: In this study, 60 apparently healthy cows under the same management conditions of the experiment, feces … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 6 Oct 2011 · 8,205 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntilithiatic Influence of Spirulina on Ethylene Glycol-Induced Nephrolithiasis in Male RatsAtef M. Al-AttarProblem statement: Nephrolithiasis or renal stone disease remains a significant health problem in the adult population. Nephrolithiasis is a recurrent disorder prominent in males. It is significant medical and surgical problem because of incidence, recurrence and severe consequences. The present day medical management of nephrolithiasis is either costly or not without side effects. Invasive procedures for the treatment of nephrolithiasis … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 70,641 accessesView PDFCite
Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,962 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,164 accessesView PDFCite