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20 articles for “Cell Dynamics”
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Research ArticleOpen accessIn the abstractIn silico Assessment of the Arg85Trp Glucokinase Mutation EffectsFaiza Bouldjennet, Souhila Bouaziz-Terrachet, Malha Azzouz, Rachida RaacheMaturity Onset Diabetes of the Young (MODY) is a heterogeneous group of autosomal dominantly inherited, young-onset β-cell disorders that account for approximately 2% of non-insulin-dependent diabetics in Europe. MODY2 or GCK-MODY is caused by inactivating heterozygous mutations in the glucokinase. Linkage of MODY to the Arg85Trp GCK mutation, among Algerian diabetic patients has been established in our previous research. The … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,808 accessesView PDFCite
EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,166 accessesView PDFCite
Research ArticleOpen accessIn the abstractHOMOLOGY MODELING AND MOLECULAR DYNAMICS STUDIES OF EC1 DOMAIN OF VE-CADHERIN TO ELUCIDATE DOCKING INTERACTION WITH CADHERIN-DERIVED PEPTIDEVivitri Dewi Prasasty, Usman Sumo Friend Tambunan, Teruna Jaya SiahaanVE-cadherin is a protein in the cadherin family that is found at the adherens junctions of the microvessel endothelial cells of the Blood-Brain Barrier (BBB). It is recognized as the homotypic cell adhesion molecules and there is limited structural information on how VE-cadherins mediate cell-cell adhesion. It has been shown that the EC1 domain of cadherins is important for the … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 25 Jun 2014 · 7,530 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Buoyancy Force in Computational Fluid Dynamics Simulation of a Two-Dimensional Continuous Ohmic Heating ProcessElzubier A. Salih, Thomas S.Y. Choong, S. Y. Sergie et al.Problem statement: Earlier work on ohmic heating technique focused on viscous food and foods containing solid particles. In this study, the use of ohmic heating on sterilization of guava juice is carried out. Computational fluid dynamics is used to model and simulate the system. Approach: Investigate the buoyancy effect on the CFD simulation of continuous ohmic heating systems of fluid … …American Journal of Applied Sciences, Vol. 6, Issue 11 · 30 Nov 2009 · 7,833 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Heat Transport in a Proton Exchange Membrane (PEM) Fuel CellE. Afshari, S.A. JazayeriIn this study a two-phases, single-domain and non-isothermal model of a Proton Exchange Membrane (PEM) fuel cell has been studied to investigate thermal management effects on fuel cell performance. A set of governing equations, conservation of mass, momentum, species, energy and charge for gas diffusion layers, catalyst layers and the membrane regions are considered. These equations are solved numerically in … …American Journal of Applied Sciences, Vol. 6, Issue 1 · 31 Jan 2009 · 7,342 accessesView PDFCite
Research ArticleOpen accessIn the abstractModelling and Analysis of Voltage Mode Controlled Luo ConverterDivya Navamani Jayachandran, Vijayakumar Krishnaswamy, Lavanya Anbazhagan, Karthikeyan DhandapaniThis paper presents the analysis of open loop power stage dynamics relevant to voltage mode control for elementary Luo DC-DC converter for certain specific applications like Hybrid Electric Vehicles, fuel cell vehicles. A comparative analysis is carried out on positive output super lift series of converters to evaluate voltage gain, output voltage ripple, stresses on the switches and efficiency. The … …American Journal of Applied Sciences, Vol. 12, Issue 10 · 7 Nov 2015 · 7,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractMULTI-STATE MODELS OF HIV/AIDS BY HOMOGENEOUS SEMI-MARKOV PROCESSZelalem Getahun DessieMulti-state stochastic models are useful tools for studying complex dynamics such as chronic diseases. The purpose of this study is to determine factors associated with the progression between different stages of the disease and to model the progression of HIV/AIDS disease of an individual patient under ART follow-up using semi-Markov processes. A sample of 1456 patients has been taken from … …Current Research in Biostatistics, Vol. 4, Issue 2 · 11 Aug 2014 · 8,209 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of Frequency Mode inside an Open Cavity for Different Shape RatioHallek Khouloud, Mourad Bouterra, Afif El Cafsi et al.A number of studies have referred to the existence of a vortex cell within an urban street canyon. The understanding of vortex dynamics or vorticity distribution is a such configuration is of great interest. This configuration was simulated by the interaction between a boundary layer and a cavity. Experimental characterization of the vortex structures evolution was developed by the technique … …American Journal of Applied Sciences, Vol. 5, Issue 11 · 30 Nov 2008 · 6,843 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordVirus Dynamics in VivoGuang Wu, Shaomin YanIn this study, we model the interaction among antibody, virus, host cell, immune cell and normal cell as random collisions, because antibody and virus are unlikely to have efficient driving systems. Then we use the model II of waiting times to analyze the collision between antibody and virus with a certain number of normal cells, and use the Monte-Carlo simulation … …American Journal of Infectious Diseases, Vol. 1, Issue 4 · 31 Dec 2005 · 6,273 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordTime-Marching Method for Computations of High-Speed Compressible Flow on Structured and Unstructured GridK.C. Ng, M.Z. Yusoff, K. Munisamy et al.The development of Computational Fluid Dynamics (CFD) compressible codes for 2D structured quadrilateral grid and 3D unstructured hexahedral grid is described. The high-speed flow in a nozzle blade cascade is predicted numerically by solving the 2D/3D Euler Equations in a coupled manner. The new finite volume CFD solvers employ second-order accurate central differencing scheme for spatial discretization and multi-stage Runge-Kutta … …American Journal of Engineering and Applied Sciences, Vol. 1, Issue 2 · 30 Jun 2008 · 7,348 accessesView PDFCite