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25 articles for “BIM”
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Research ArticleOpen accessIn the author namesNEWER DRUGS FOR VISCERAL LEISHMANIASIS: A REVIEWKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Visceral Leishmaniasis (VL) is one of the most neglected tropical diseases worldwide. The diagnosis and treatment of this disease is quite complex. Sodium Antimony Gluconate (SAG) which used to be a very effective treatment has now developed resistance and is potentially a cardio-toxic drug. Pentamidine has now been discarded because of adverse effect of diabetes mellitus. Amphotericin-B is an effective … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 5 May 2014 · 7,133 accessesView PDFCite
Research ArticleOpen accessIn the author namesASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,073 accessesView PDFCite
Research ArticleOpen accessIn the author namesLeishmania donovani: Immunomodulatory Role of 63KDa Leishmania Antigen in the Promotion of IFN-gamma Response (VL vs HIV-VL Co-infection)Pranati, Sanjiva Bimal, K. Pandey et al.Cytokine behavior of T-lymphocytes is not very clear when a patient is co-infected with Leishmania donovani and HIV. To achieve this we studied groups of patients comprising of VL infected, HIV infected and HIV-VL co-infected cases. As compared to lone infections by either of the infecting agent, the co-infection cases showed greatly diminished CD4 T-cell counts and slightly enhanced values … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,000 accessesView PDFCite
Research ArticleOpen accessIn the author namesTowards Identifying Immunogenic Targets in Visceral Leishmaniasis: Role of 17kDa and 63kDa PhosphoproteinsShubhankar K Singh, Sanjiva Bimal, Diwakar S. Dinesh et al.We observed predominant phosphorylation at Protein Kinase C (PKC-α) residue in seven immunoreactive proteins of virulent Leishmania donovani parasites. These phosphoproteins were tested for their ability to stimulate T-cells for secretion of Macrophage Migration Inhibition Factor (MIF) in comparision to crude soluble antigen in Visceral Leishmaniasis (VL) patients. Two of these phosphorylated L. donovani antigens led Leishmania to present these … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,756 accessesView PDFCite
Research ArticleOpen accessIn the author namesComparative Evaluation of Aqueous and Freeze Dried Antigen for Sero-diagnosis of VL and PKDL Cases by DATSanjiva Bimal, Shubhankar K. Singh, P. K. Sinha et al.The efficacy of aqueous and freeze dried (FD) antigen was evaluated by direct agglutination test (DAT) for sero-diagnosis of visceral leishmaniasis. A total of 16 samples collected from 5 confirmed Kala-azar (KA) cases, 6 cases 2 each of filariasis, malaria, leprosy and 5 non-endemic healthy subjects were used in determination of cut off titre of both the antigens in DAT. … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,834 accessesView PDFCite
Research ArticleOpen accessIn the abstractBuilding Information Modeling for Indoor Environmental Performance AnalysisYaik-Wah LimThere are increasing numbers of Building Information Modeling (BIM) software available nowadays which change the working methods in Architecture, Engineering and Construction (AEC) industry. From the stages of building design development to post-occupancy management, BIM plays an essential role in collaboration among multi-discipline professions, time and cost saving, fabrication and construction as well as facilities management. With the arising concern … …American Journal of Environmental Sciences, Vol. 11, Issue 2 · 29 Apr 2015 · 7,992 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring Self-Sovereign Identity Through a Digital Transcript Proof-of-ConceptNaphat Khajohn-Udomrith, Ittipon RassameerojCredential forgery presents a significant threat to the integrity of academic and employment documents. While Self-Sovereign Identity (SSI) and Verifiable Credentials (VC) offer a decentralized alternative, existing solutions often struggle to balance institutional trust with holder privacy. This paper proposes a novel, dual-layered architectural framework for digital transcripts. We implement a strategic bimodal DID approach, utilizing did:web for the issuing … …Journal of Computer Science, Vol. 22, Issue 5 · 21 May 2026 · 1,487 accessesView PDFCite
Research ArticleOpen accessIn the abstractAI-Guided Anatomical Landmark and Abnormality Detection for Autonomous Endoscopy ExaminationMd Shakhawat Hossain, Munim Ahmed et al.Aabakken, L., Barkun, A. N., Cotton, P. B., Fedorov, E., Fujino, M. A., Ivanova, E., Kudo, S., Kuznetzov, K., De Lange, T., Matsuda, K., Moine, O., Rembacken, B., Rey, J., Romagnuolo, J., Rösch, T., Sawhney, M., Yao, K., & Waye, J. D. (2014). Standardized endoscopic reporting. Journal of Gastroenterology and Hepatology, 29(2), 234–240. https://doi.org/10.1111/jgh.12489 Aliyi, S., Dese, K., & Raj, … …Journal of Computer Science, Vol. 20, Issue 8 · 29 May 2024 · 6,783 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Purified Tick Saliva Toxins on Various Bio-Molecules in Blood Serum, Liver and Muscles of Albino MiceNidhi Yadav, Ravi Kant UpadhyayIn the present study, salivary toxins from Rhipicephalus microplus were isolated and purified on a Sepharose CL 6B 200 gel column at a constant flow rate with regular fractions of 5 mL/min. Pooled fractions were lyophilized and LD50 was then determined in albino mice. The LD50 value of the protein toxin of Rhipicephalus microplus was found 36.11 mg/kg body weight … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 1 · 30 Dec 2023 · 5,354 accessesView PDFCite
Research ArticleOpen accessIn the abstractMeasurement of Cooling Load-Based Occupant Behavior in Under-Actuated Zones: A Time-Variance ApproachYaddarabullah, Yusuf Maulana Akbar, Aedah Binti Abd Rahman, Amna SaadThis research is dedicated to the enhancement of Heating, Ventilation, and Air-Conditioning (HVAC) systems through an innovative investigation of occupant behavior within under-actuated zones. These zones are strategically positioned to elevate indoor air quality and comfort through the intelligent utilization of HVAC systems. However, accurately measuring the cooling loads within these zones, which are inherently influenced by the presence of … …American Journal of Applied Sciences, Vol. 20, Issue 1 · 11 Dec 2023 · 6,158 accessesView PDFCite