14 results for “B. W. McBride”

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Research ArticleOpen accessIn the author namesButyrate-Mediated Genomic Changes Involved in Non-Specific Host Defenses, Matrix Remodeling and the Immune Response in the Rumen Epithelium of Cows Afflicted with Subacute Ruminal AcidosisLouis Dionissopoulos, Anne Hermen Laarman, Ousama AlZahal et al.Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by butyrate have not been defined. The objective of this study was to define the inflammatory-related genomic changes … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 10 Jan 2013 · 8,059 accessesView PDF Cite

Research ArticleOpen accessIn the author namesA Characterization of Inflammatory and Structural Markers within the Rumen Epithelium During Grain-Induced Ruminal Acidosis in Lactating Dairy CattleL. Dionissopoulos, M. A. Steele, O. AlZahal et al.The objective of this study was to characterize the mRNA and protein expression of inflammatory and structural genes in the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattle. A total of 16 rumen-fistulated, lactating Holstein dairy cattle (618±35 kg of body weight, 221±32 days in milk) were used in a randomized complete block design study. All cattle were … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 3 · 19 Sep 2012 · 8,035 accessesView PDF Cite

Research ArticleOpen accessIn the author namesAdaptation to High Grain Diets Proceeds Through Minimal Immune System Stimulation and Differences in Extracellular Matrix Protein Expression in A Model of Subacute Ruminal Acidosis in Non-lactating Dairy CowsB. W. McBride, O. AlZahal, M. A. Steele, L. DionissopoulosProblem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with SARA seem to remodel and adapt their epithelium to accommodate the stresses imposed by SARA, but … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 25 Jul 2012 · 8,118 accessesView PDF Cite

Research ArticleOpen accessIn the author namesPlasma Fatty Acid Profile of Gestating Ewes Supplemented with FishmealMamun M. Or-Rashid, Rebecca Fisher, Niel Karrow et al.Problem statement: The very long chain n-3 polyunsaturated fatty acids (>18C) cannot be adequately synthesized by ruminant tissues to meet their requirements; therefore, their concentration in body depends on the supply through feed. It may be possible to improve the essential fatty acid status of ruminant animals, during gestation by manipulating the maternal diet with Fishmeal (FM). The objectives of … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 9 Jul 2012 · 8,219 accessesView PDF Cite