15 articles for “Autism spectrum disorder”

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Research ArticleOpen accessIn the abstractA Coding Schema-Based Mobile System for Children With ASD in MauritaniaCheikhne Mohamed Mahmoud Seyidi, Ahmed Mohameden, Mohamed Lamine Diakité, Mohamedade Farouk NanneChildren with Autism Spectrum Disorders (ASD) in many African countries face persistent barriers, including limited diagnostic awareness, scarce specialized resources, and the absence of educational interventions adapted to local contexts. In Mauritania, these challenges are exacerbated by the extreme centralization of autism services, with only two care centers available nationwide. Unlike existing ASD interventions that rely on imported pedagogical models … …Journal of Computer Science, Vol. 22, Issue 5 · 25 May 2026 · 1,312 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Learning Mechanism to Improve Skills Acquisition for Autistic Children in MauritaniaCheikhne Mohamed Mahmoud Seyidi, Cheikhane Seyed, Mohamed El Moustapha El Arby et al.The learning of autistic children is an issue for care and treatment centers for children with autism spectrum disorder, however many studies seek to find learning mechanisms and models in order to facilitate their social integration. The aim of this study is to propose a learning mechanism based on the analysis and annotation of a corpus video filmed during the … …Journal of Computer Science, Vol. 19, Issue 9 · 23 Aug 2023 · 5,618 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAltered Sulfur Amino Acid Metabolism In Immune Cells of Children Diagnosed With AutismJung H. Suh, William J. Walsh, Woody R. McGinnis et al.Autism Spectrum Disorder (ASD) is a behaviorally defined neurodevelopmental disorder whose etiology is poorly understood. Recent studies have shown that autistic children may be experiencing increased inflammation and oxidative stress. Altered immune regulation may be one contributing factor to inflammation and oxidative stress in autistic children. Sulfur amino acid (SAA) metabolism plays a critical role in regulating blood leukocyte functions … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 10,789 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid OxidationTeresa A. Evans, Sandra L. Siedlak, Liang Lu et al.Oxidative damage has been documented in the peripheral tissues of autism patients. In this study, we sought evidence of oxidative injury in autistic brain. Carboxyethyl pyrrole (CEP) and iso[4]levuglandin (iso[4]LG)E2-protein adducts, that are uniquely generated through peroxidation of docosahexaenoate and arachidonate-containing lipids respectively, and heme oxygenase-1 were detected immunocytochemically in cortical brain tissues and by ELISA in blood plasma. Significant … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,724 accessesView PDF Cite