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48 results for “Alzheimer disease”

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Research ArticleOpen accessEvery word in the titleSilkworm Pupae Protect Against Alzheimer’s DiseaseJintanaporn Wattanathorn, Supaporn Muchimapura, Artit Boosel et al.Silkworm (Bombyx mori) pupae have long been used as food and medicine in Asian countries. It is reputed for the treatment of numerous neurological disorders related to oxidative stress including stroke. Therefore, we hypothesized that silkworm pupae could attenuate memory impairment and neurodegeneration in Alzheimer’s disease. In the present study, we determined the effect of silkworm pupae on the neurodegeneration … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 16 Aug 2012 · 9,697 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNeuroprotective Effect against Alzheimer's Disease of Porcine Brain ExtractWipawee Thukham-Mee, Jintanaporn Wattanathorn, Supaporn Muchimapura, Chuleratana BunchonglikitkulProblem statement: Despite the increasing importance of Alzheimer’s disease, no effective therapeutic strategy is available. Therefore, neuroprotective strategy is still required. Recent findings show that numerous substances possessing antioxidant can improve neurodegeneration and memory impairment. Based on the antioxidant effect and its reputation to serve as brain tonic in traditional folklore, we hypothesized that porcine brain extract could mitigate neurodegeneration … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 8,243 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImproved Application of Paraconsistent Artificial Neural Networks in Diagnosis of Alzheimer's DiseaseHelder F.S. Lopes, Jair M. Abe, Paulo A.M. Kanda et al.Problem statement: The visual analysis of Electroencephalogram (EEG) activity has shown useful as a complementary tool in Alzheimer Disease (AD diagnosis) when the diagnosis remains uncertain, in addition to be used in some clinical protocols. However, this analysis is subject to the inherent equipment imprecision, biological artifact, electrical records, and subjective physician interpretation of the visual analysis variation. The Artificial … …Neuroscience International, Vol. 2, Issue 1 · 6 Oct 2011 · 12,061 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNasal Administration of Quercetin Liposomes Improves Memory Impairment and Neurodegeneration in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Supaporn Muchimapura, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the development of protective strategy against Alzheimer’s Disease (AD) is increasing its importance due to the high prevalence of AD, a limitation of therapeutic efficacy and its high impacts on economic and social aspects. The development of the preventive and therapeutic strategy to protect against the path physiology induced by free radicals in AD from antioxidant … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 7,743 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNeuroprotective Effect of Quercetin Encapsulated Liposomes: A Novel Therapeutic Strategy against Alzheimer’s DiseaseW. Phachonpai, J. Wattanathorn, S. Muchimapura et al.Problem statement: The prevalence of Alzheimer’s disease is increasing but the efficacy of treatment is still very limited due to various factors including the blood brain barrier. Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of disease. In addition the burden of blood brain barrier can be overcome by nasal administration and vesicle-carrier mediated delivery system. … …American Journal of Applied Sciences, Vol. 7, Issue 4 · 30 Apr 2010 · 9,449 accessesView PDFCite
Literature ReviewOpen accessEvery word in the titleA Comprehensive Survey on Tools for Effective Alzheimer’s Disease DetectionN. Vinutha, G. U. Vasanthakumar, P. Deepa Shenoy, K. R. VenugopalNeuroimaging is considered as a valuable technique to study the structure and function of the human brain. Rapid advancement in medical imaging technologies has contributed significantly towards the development of neuroimaging tools. These tools focus on extracting and enhancing the relevant information from brain images, which facilitates neuroimaging experts to make better and quick decision for diagnosing enormous number of … …Neuroscience International, Vol. 9, Issue 1 · 4 Oct 2017 · 10,232 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleDeep Learning in Early Alzheimer’s Disease’s Detection: A Comprehensive Survey of Classification, Segmentation and Feature Extraction MethodsRubab Hafeez, Sadia Waheed, Syeda Aleena Naqvi et al.Alzheimer’s disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimer’s disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8-4.4 years after the first clinical indication. Advancements in computing and information technology have led to many techniques for studying Alzheimer's disease. Early identification and therapy are crucial for preventing Alzheimer's disease, as early-onset … …Journal of Computer Science, Vol. 21, Issue 5 · 26 Apr 2025 · 5,765 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImage-Based Alzheimer's Disease Detection Using Pretrained Convolutional Neural Network ModelsNasser AlsadhanAlzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent cause of dementia. Although there is presently no treatment for Alzheimer's disease, scientific trials are ongoing to discover drugs to combat the condition. Treatments … …Journal of Computer Science, Vol. 19, Issue 7 · 28 Jun 2023 · 5,909 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,955 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProduction and Characterization of Exopolysaccharide from Novel Bacillus sp. M3 and Evaluation on Development Sub-Chronic Aluminum Toxicity Induced Alzheimer’s Disease in Male RatsMohsen M.S. Asker, Abeer Y. Ibrahim, Manal G. Mahmoud, Saher S. MohamedThe number of patients suffering from Alzheimer’s Disease (AD) all over the world is rising continually and becomes one of the biggest challenges for most societies throughout the world. The potential of peripheral biochemical markers as complementary tools in the neuron-phsychiatric evaluation of these patients has claimed further attention. The aims of our study were to isolate the bacteria that … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 31 May 2015 · 7,216 accessesView PDFCite