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20 results for “Acute Exposure”
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Research ArticleOpen accessIn the abstractAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,791 accessesView PDFCite
Research ArticleOpen accessIn the abstractTrace Elements Distribution in the Brain of Stressed RatsZerrouk Kamal, Mohamed Najimi, Mohammed Chigr et al.Because of their ability to modulate the Gamma Aminobutyric Acid (GABA) a receptor complex, the principal aim of the current work is to assess two essential heavy metals: Iron (Fe) and zinc (Zn) by atomic absorption in different brain areas of stressed rats. To do so, we investigated the effect of acute immobilization stress (single 1-hour session) on the distribution … …Neuroscience International, Vol. 3, Issue 2 · 14 Sep 2012 · 7,277 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Leaves Extract Attenuates Male Sexual DysfunctionWipawee Thukhammee, Supaporn Muchimapura, Sitthichai Iamsa-ard et al.Problem statement: At present, the novel agent that is effective, cheap and easy to approach for treating male sexual dysfunction is required due to the current poor therapeutic efficacy. Though Moringa oleifera is reputed for aphrodisiac activity in traditional folklore, no scientific evidence is available. Therefore, we aimed to determine the effect of M.oleifera leaves extract on male sexual behaviors … …Neuroscience International, Vol. 3, Issue 1 · 1 Sep 2012 · 32,897 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydrobiopterin (BH2): Key Determinant in Influencing Arginine Mediated Endothelial Tolerance and DysfunctionSrinidi Mohan, Harsh Patel, Jorge Bolinaga et al.The redox-sensitive tetrahydrobiopterin (BH4) is an essential cofactor that is required by endothelial Nitric Oxide Synthase (eNOS) for L-arginine (ARG) mediated Nitric Oxide (NO) generation. Oxidation of BH4 causes cofactor insufficiency and uncoupling of eNOS, resulting in product switching from NO to O2⋅– production. Here we tested the hypothesis that eNOS uncoupling is not simply a consequence of BH4 insufficiency, … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,348 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntervened 2-Tier Poisson Distribution for Understanding Hospital Site InfectivityR. ShanmugamProblem statement: Whether it is a surgical site or medical treatment at a hospital site, the nurses in particular and the entire medical team including surgeons/physicians in general undergo a risk of being infected ironically by the patients whom they intend to disinfect. There are 2-tiers of patients at the site. One type consists of patients who are internally and … …International Journal of Research in Nursing, Vol. 3, Issue 1 · 31 Mar 2012 · 6,925 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Age Thermal Conditioning Improves Broiler Chick's Response to Acute Heat Stress at Marketing AgeAhmed M. Hassan, P. Gopal ReddyProblem statement: Acute heat stress at marketing age especially in broiler chickens raised in open houses with reduced means of heat exchange leads to economic losses. The objective of this study was to determine beneficial effects of early age thermal conditioning in reducing adverse effects of acute heat stress and decrease losses. Approach: Ninety one day-old broiler chicks were randomly … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 17 Feb 2012 · 8,660 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Prophylactic and Therapeutic Effects of Silymarin on Diazepam-Induced Hepatotoxicity in CatsBahman Mosallanejad, Reza Avizeh, Hossien NajafzadehProblem statement: Diazepam is commonly administered for seizure control and appetite stimulant in cats. Cats may develop acute fatal hepatic necrosis after receiving oral diazepam for several days. The aim of this study was to detect the protective action of silymarin on diazepam-induced hepatotoxicity in cats. Approach: About 25 healthy cats were randomly allotted to five equal groups. Animals in … …American Journal of Applied Sciences, Vol. 8, Issue 9 · 29 Jul 2011 · 7,420 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Intracerebroventricular Administration of W-7, A Calmodulin Inhibitor, Attenuate the Development of Morphine Tolerance in RatsGholamreza Sepehri, Vahid Sheibani, Afrooz Azarang et al.Problem statement: The present study was performed to determine the effect of Intracerebroventricular (ICV) administration of W-7, a specific calmodulin inhibitor, on the analgesic effect and development of tolerance to antinociceptive effect of acute and chronic morphine administration respectively. Approach: This study was carried out on male wistar rats, weighing 200-250 g. For acute experimental protocol, Morphine was injected intraperitonealy … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 7,752 accessesView PDFCite
Research ArticleOpen accessIn the abstractStressors Influence on Salmonella enterica Serovar Enteritidis Colonization in BroilersE. S. Soliman, E. Taha, K. D. Infante et al.Problem statement: Poultry industry usually exposing birds to a variety of actions and stressors includs fasting for gastrointestinal emptying before transportation and where birds are often exposed to high environmental temperature during the summer months. These environmental stressors may have influences on bird performance and susceptibility to pathogens such as Salmonella enteritidis by altering the intestinal micrbiota and changes in … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 3 · 12 Sep 2009 · 7,187 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Mathematical Modeling Approach to Characterize Hormesis, Caloric Restriction and Toxicity in Mortality Data from Toxicity StudiesPatricia J. NeafseyThe mortality of a population reflects the combined effects of natural aging with environmental insults (e.g. toxicant exposure, caloric restriction, over feeding, infections, etc.). No single endpoint, such as carcinogenesis, completely describes toxicant-induced effects in laboratory animals. Mathematical models of mortality and time-dependent exposure to toxicants can yield indices of net injury from all causes. With careful manipulation of diet … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,160 accessesView PDFCite