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30 results for “Acetylcholine”
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Research ArticleOpen accessIn the abstractMechanism of Mulberry's Effect on Intestinal Flora and MotilityHuizhen Zhao, Shijing Xie, Yuwen Li et al.Studies have indicated that mulberry consumption promotes intestinal motility and alleviates constipation, but the specific mechanism remains unclear. This study adopted a constipation mouse model to empirically analyze the effects of mulberry on intestinal motility, gut microbiota composition, and neurotransmitter levels, aiming to elucidate its mechanism of action. Key findings are as follows: 1) Compared with the model group, the … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 1,189 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Exposure of Pesticides to Honeybees: A Global Threat to Food SecurityHalima Sadia, Pratik Raj Karki, Mansura Afroz et al.The pivotal role of honeybees as global pollinators underscores their significance in ecological and agricultural systems. However, the beekeeping industry faces a significant challenge due to the improper utilization of pesticides, resulting in adverse effects on honeybee populations. This comprehensive review endeavors to investigate the toxicity of pesticides to honeybees, examining the various routes of exposure. Furthermore, it aims to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 20 Jan 2024 · 6,058 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction and Characterization of Exopolysaccharide from Novel Bacillus sp. M3 and Evaluation on Development Sub-Chronic Aluminum Toxicity Induced Alzheimer’s Disease in Male RatsMohsen M.S. Asker, Abeer Y. Ibrahim, Manal G. Mahmoud, Saher S. MohamedThe number of patients suffering from Alzheimer’s Disease (AD) all over the world is rising continually and becomes one of the biggest challenges for most societies throughout the world. The potential of peripheral biochemical markers as complementary tools in the neuron-phsychiatric evaluation of these patients has claimed further attention. The aims of our study were to isolate the bacteria that … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 31 May 2015 · 7,216 accessesView PDFCite
Research ArticleOpen accessIn the abstractTotal Synthesis of Endangered Frog Alkaloid ’Epibatidine’, A Potent Analgesic of the FutureN.R. Dhatrak, M.G. Kulkarni’Epibatidine’ is a nicotinic alkaloid’, was first discovered in the skin of neotropical poisonous frog, ’Epipedobates tricolor’ found in Ecuador. John Daly in 1974 first isolated a trace quantity of this alkaloid by scarifying several frogs. With the evolution of NMR techniques the structure of this alkaloid was reported in 1992. An year after, Nobel Laureate Prof. E.J. Corey, devised … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 17,112 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Extract Mitigate Vascular DementiaPratchaya Kaewkaen, Jintanaporn Wattanathorn, Terdthai Thong-Un et al.To date, Vascular Dementia (VaD) is the second most commonly found dementia following Alzheimer�s disease. Though VaD is still increasing its importance, the therapeutic efficacy is still not in satisfaction level. Therefore, the searching for an acceptable cheap and safe neuroprotective agent is in a great demand. Based on the neuroprotective and cognitive enhancing effects in alcohol neurotoxicity of mulberry … …American Journal of Applied Sciences, Vol. 9, Issue 11 · 1 Sep 2012 · 6,967 accessesView PDFCite
Research ArticleOpen accessIn the abstractZerumbone: A Natural Compound with Anti-Cholinesterase ActivityAhmad Bustamam, Siddig Ibrahim, Adel S. Al-Zubairi et al.Herbal dugs could be a new source for inhibitors of acetyl cholinesterase (anti-AChE), the key enzyme in the breakdown of acetylcholine and a new talented approach for the cure of elderly neurologically associated disorders such as Alzheimer’s disease (AD). Zerumbone (ZER) is sesquiterpene from the edible plant, Zingiber zerumbet which is known to possess tremendous biological activities. In this study, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 9,638 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and MechanismsPhillip R. Zoladz, David M. DiamondOver a century of behavioral research has shown that stress can exert both positive and negative effects on memory. We have explored the idea that the complex effects of stress on learning and memory can be characterized by hormetic- and non-hormetic dose-response functions, in which stress may either stimulate or impair brain memory mechanisms, depending, in part, on the timing … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntagonism Between Chlorpyrifos and Flaxedil in Toad and Earthworm Neuromuscular TransmissionYong-Chiang Chang, Amauri B. Bartoszeck, Samir A. Madeira, Charles I. AbramsonThe cholinesterase inhibition effect of chlorpyrifos, a commercial insecticide, was tested by its antagonism to the acetylcholine inhibition effect of flaxedil in 30 isolated nerve-sartorius muscle preparations of the toad, compared with its antagonism in 30 isolated nerve cord-body wall muscle preparations of the earthworm. Inhibition and facilitation in this antagonism were measured by changes in depolarizing rate of toad … …American Journal of Environmental Sciences, Vol. 2, Issue 2 · 30 Jun 2006 · 6,389 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Dietary Emamectin Benzoate at Recommended and Overdose Levels on the Pathophysiological Responses and Tolerability of Oreochromis niloticus at Fry StageJasmine Singha, Thangapalam Jawahar Abraham, Satyen Kumar Panda, Prasanna Kumar PatilEmamectin Benzoate (EB) has been recommended as a feed additive for the control of fish ectoparasites. This investigation examined the impact of dietary EB on physiological responses, antioxidant defence mechanisms, and histopathological changes in key organs, and on the kinetics of residue deposition and elimination in the muscle of Oreochromis niloticus fry. Fry were administered EB feeds at 50 µg … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 1 Jul 2026 · 1,469 accessesView PDFCite