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172 results for “Gene Expression”
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Research ArticleOpen accessAll words, across the recordMicrornas as Double Edged Sword in CancerBaby Joseph, Vrundha M. NairCancer is the leading causes of death world wide. Basically it can be defined as the disease of the cell. One among the mechanism of transfer of a normal cell to cancerous is the alteration in the genetic material DNA. Treatment for cancer remains as a biggest challenge. Here comes the importance of miRNAs. They are endogenous RNA which regulates … …Current Research in Bioinformatics, Vol. 2, Issue 1 · 24 May 2013 · 6,953 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordHyper-Ag-specific Ab Production in NC/Nga Mice is not associated with Deletion Polymorphism in the Promotor Region of the FcγRIIB GeneTohru Sakai, Mariko Nakamoto, Emi SutoProblem statement: NC/Nga (NC) mice produced high levels of ovalbumin (OVA)-specific IgG, IgG1 and IgG2a. We previously found deletion polymorphisms in the promoter region of fcgr2b in NC mice. To determine whether this mutation causes a hyper-humoral immune response, we generated congenic BALB/c mice carrying the NC-type fcgr2b allele (NC fcgr2b) and analyzed humoral immune response and FcγRIIB on germinal … …American Journal of Immunology, Vol. 5, Issue 3 · 31 Dec 2009 · 7,364 accessesView PDFCite