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175 articles for “susceptibility”
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Research ArticleOpen accessIn the abstractBorderline Personality Symptoms and Human Immunodeficiency Virus Risk in Alcohol and Other Drug Abusing Adolescent OffendersJessy G. Dévieux, Robert M. Malow, Rhonda Rosenberg et al.Problem statement: Incarcerated youth with borderline symptomatology represent a particularly at risk-population due to their enggement in risky behaviors. Five hundred twenty two adolescents were assessed for borderline symptomatology (MACI), engagement in risky behaviors and attitudes/knowledge. Approach:Adolescents were divided into two groups: low borderline (below the 60 scale score cutoff) and high borderline (subclinical and clinical range). Multivariate analyses were … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 7,817 accessesView PDFCite
Research ArticleOpen accessIn the abstractCancer Chemotherapy and Immune RegulationJohn Barrett, Katarina Le BlancProblem statement: Chemotherapeutic drugs have been used to treat malignancy for over 50 years, but the potential of cytotoxic agents to suppress immunity and interfere with Immunosurveillance (IS) of cancer has been largely ignored. Assuming that the immune control of the cancer had a priori already failed, the effect was not considered to have a major impact on treatment outcome. … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 40,670 accessesView PDFCite
Research ArticleOpen accessIn the abstractLack of Association of Glutathione S-transferase Gene Polymorphisms in Iranian Prostate Cancer SubjectsB. Sahar Ansari, R. Vasudevan, M. Mirinargesi et al.Problem statement: Glutathione S-transferase is super family genes that encode enzymes which involve in the detoxification of the cell and protects DNA from damage. Conflicting results was found in several studies in association with GSTT1 and GSTM1 gene polymorphisms and prostate cancer. In this study, we determined the association between the GSTT1 and GSTM1 gene polymorphism and prostate cancer in … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,279 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Resistant Coagulase-Negative Staphylococcus (CoNS) in Clinical SettingsM.A. Shorman, A.M. Atoom, N.M. Abuharfeil, A.M. Al-MajaliTo evaluate different methods for the identification of methicillin-resistant Staphylococci and their reliability, 112 Staphylococcal isolates (32 Staphylococcus aureus isolates and 80 coagulase negative Staphylococci isolates "CoNS") were collected from 118 nasal swab cultures and were subjected to three methods to detect oxacillin susceptibility of the isolates. The three methods were oxacillin disk diffusion method; the Epsilometer- test (E-test) and … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,978 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnvironmental Factors and Limbic Vulnerability in Childhood AutismRichard LatheThe rise in prevalence of autism spectrum disorders (ASD) is suggestive of a new etiology. Diagnostic substitution alone is unlikely to account for the increase, while genetic association with detoxification gene alleles points to an environmental contribution. Subtle structural anomalies in the ASD brain are widespread but limbic damage seems important for the development of behaviors diagnostic of ASD. The … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,680 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Frequency of Polymorphisms affecting Lead and Mercury Toxicity among Children with AutismShannon Rose, Stepan Melnyk, Alena Savenka et al.Individual risk of developmental neurotoxicity with exposure to environmentally relevant levels of lead and mercury is likely to be determined by genetic susceptibility factors as well as additive interactions with other environmental pollutants, cumulative dose, and the developmental stage of exposure. The apparent increase in autism diagnosis over the last 15 years has enhanced interest in the possibility that an … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,524 accessesView PDFCite
Research ArticleOpen accessIn the abstractT-2 Toxin Regulated Ganoderma lucidum Induced Cytokine ReleaseKazem Ahmadi, Majid RiazipourThe water-soluble extract of Ganoderma lucidum (Reishi) has been used as immunomodulator to stimulate spleen cells proliferation and cytokine expression. It has also been shown that at some level of exposure, T-2 toxin typically act as immunosuppressive agent and can increase disease susceptibility. The aim of this study was to investigate the effect of T-2 toxin on cytokine production by … …American Journal of Immunology, Vol. 4, Issue 1 · 31 Mar 2008 · 7,541 accessesView PDFCite
Research ArticleOpen accessIn the abstractAccumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell LinesAlessandra Pani, Claudia Norfo, Claudia Abete et al.Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie in sheep, revealed abnormal accumulation of cholesterol esters in brains and in ex vivo skin fibroblasts from genetically scrapie-susceptible, as compared to sheep with resistant genotype. We now report that PBMCs isolated from scrapie-susceptible sheep, as well as mouse neuroblastoma cell lines persistently infected with two different … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,960 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Slope Geometry on Flowslide OccurrenceChiara DeangeliThe paper reports a study aimed to the prediction of susceptibility to flowslide of granular soil slopes as a consequence of the in situ state of stress. In particular, the slope geometry has been investigated as a factor influencing the initial state of stress. For this purpose the results of numerical models, performed by a finite different approach (FLAC), allowed … …American Journal of Environmental Sciences, Vol. 3, Issue 3 · 30 Sep 2007 · 6,975 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtein Molecular Structures, Protein SubFractions, and Protein Availability Affected by Heat Processing: A ReviewPeiqiang YuThe utilization and availability of protein depended on the types of protein and their specific susceptibility to enzymatic hydrolysis (inhibitory activities) in the gastrointestine and was highly associated with protein molecular structures. Studying internal protein structure and protein subfraction profiles leaded to an understanding of the components that make up a whole protein. An understanding of the molecular structure of … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 8,294 accessesView PDFCite