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228 results for “Toxicity”

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Research ArticleOpen accessIn the abstractEvaluation of Effluent from the University of Nigeria, Nsukka Wastewater Treatment Plant for Irrigation PurposesEmmanuel Amagu Echiegu, Ogochukwu Ruth Eya, Samson Nnaemeka Ugwu, Boniface UgwuishiwuThis study was carried out to determine the suitability of effluents from the University of Nigeria, Nsukka (UNN) sewage treatment facility for irrigation purposes. The result shows that, from the point of view of ECw, SAR, solids, organic matter content, ion toxicity and nutrients (except Phosphate), the UNN wastewater treatment plant effluent can be safely used for irrigation, especially under … …American Journal of Environmental Sciences, Vol. 12, Issue 2 · 21 Apr 2016 · 8,096 accessesView PDFCite
Research ArticleOpen accessIn the abstractChemical Mutagenesis for Improvement of Production of a Biologically Active Extracellular Polymeric Substance by Halomonas xianhensis SUR308Jhuma Biswas, Amal K. PaulA moderately halophilic bacterium, Halomonas xianhensis SUR308 (Genbank Accession No. KJ933394) isolated from solar saltern of Surala, Odisha, India was found to produce significant amount of a biologically active extracellular polymeric substances (EPS). Under optimized cultural conditions, the strain was able to produce 7.05 g L-1 of EPS after 8 days of incubation under shake culture. To enhance the EPS … …Current Research in Microbiology, Vol. 7, Issue 1 · 1 Apr 2016 · 15,926 accessesView PDFCite
Research NotesOpen accessIn the abstractPolymerisation and Oxidation of Docosahexaenoic AcidBrian Mundell Ross, Shelly Lynn Browning, Adrian McKeeOils rich in polyunsaturated fatty acids, such as linseed oil, can oxidise to form polymers. These can be used as protective coatings and act as an alternative to those derived from petrochemicals. Such renewable source oils usually require the addition of metal ions as catalysts of the polymerisation process and/or the partial pre-oxidation of the oil before use. We hypothesised … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 1 · 11 Dec 2015 · 7,621 accessesView PDFCite
HypothesisOpen accessIn the abstractCan Anthocyanins be Part of the Metal Homeostasis Network in Plant?Marco LandiAnthocyanins are a class of flavonoids with a high level of diversification and likely the most studied pathway of secondary metabolism in Plantae. Anthocyanins have raised a growing interest due to the huge variability of their chemical structures and the more new anthocyanins are isolated from plants, the more questions on their evolutionary and ecological meaning they raise. Antioxidant, photoprotection … …American Journal of Agricultural and Biological Sciences, Vol. 10, Issue 4 · 9 Dec 2015 · 8,573 accessesView PDFCite
Research ArticleOpen accessIn the abstractStatus of Heavy Metals in Water and Sediment of the Meghna River, BangladeshMahmud Hassan, Mirza A.T.M. Tanvir Rahman, Badhan Saha, Abdul Kadir Ibne KamalThe pollution of river water and sediments by heavy metals has assumed serious problems due to their toxicity and accumulative behavior. The present study has been undertaken to assess the levels of heavy metals and the extent of pollution in the surface water and sediments from the Meghna river. Water and sediment samples were collected by the Standard Methods and, … …American Journal of Environmental Sciences, Vol. 11, Issue 6 · 24 Nov 2015 · 12,843 accessesView PDFCite
Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,710 accessesView PDFCite
EditorialOpen accessIn the abstractAMYOTROPHIC LATERAL SCLEROSIS: HOW TO UNDERSTAND SUCH DIVERSE AND SO ENTANGLED PHYSIOPATHOLOGY?Carlos Henrique Melo Reis, Marco Orsini, Marco Antônio Araujo Leite et al.When in 1865, JeanMartin Charcotreported patients with progressive muscular atrophysuperimposedwith spasticity of inexorable evolution as result of combinedlesions of the anterior horn and lateral column of the spinal cord, hecertainly inaugurated an attempt on the comprehension of one of the mostcomplexes neurological clinical conditions, which until today persists withimmense voids on their comprehension, regardless of the enormous advancesachieved. Astime went … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Feb 2015 · 7,151 accessesView PDFCite
Research ArticleOpen accessIn the abstractReverse Pharmacology-A Paradigm Shift for Drug Discovery and DevelopmentAshok D.B. VaidyaThe current scenario of drug discovery and development is facing a model perturbation, despite significant advances in genomics, proteomics, metabolomics, combinatorial chemistry and high through put assays. There is an urgent need of a paradigm shift in approaches to drug discovery. Natural products of Ayurveda offer a vast potential for novel phytomolecules with clinical activity. In India, Ayurveda is availed … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 15,404 accessesView PDFCite
Research ArticleOpen accessIn the abstractCrosstalk between Oxidative Stress Signaling and HER2 Pathway in Breast CancerVanessa Jacob Victorino, Adriano Martin Felis Aranome, Fernanda Carolina de Campos et al.About 20% of breast cancer patients overexpress the Human Epidermal growth factor Receptor-2 (HER2), also known as ErbB2. HER2-overexpression is associated with enhanced tumor malignancy and its overexpression is related to specific target therapy against breast tumors and other cancers. HER2-mediated pathways in tumor cells act on behalf of the tumor conferring aggressive characteristics. Several reports demonstrated the occurrence of … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 8,041 accessesView PDFCite
Research ArticleOpen accessIn the abstractTRANSPIRATION INFLUENCES CADMIUM UPTAKE BY BABY LEAF SPINACH (SPINACIA OLERACEA L.)Carlo Chehine, Paul Holford, Oula Ghannoum et al.Cadmium (Cd) is a toxic heavy metal whose concentration in soils is rising. This study investigated the effect of transpiration on Cd uptake by plants using soil conditions akin to those experienced by field crops. Two experiments were performed using baby leaf spinach (Spinacia oleracea L.) grown in soil containing Chloride (Cl) at a typical concentration of 70 mg kg-1. … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 4 · 23 Dec 2014 · 8,066 accessesView PDFCite