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182 articles for “Diabetes”

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Research ArticleOpen accessIn the abstractRandomized Clinical Stroke Trials in 2009Meheroz H. RabadiProblem statement: Stroke ranks as the leading cause of serious, long-term disability and death world-wide. It is estimated direct and indirect cost of stroke for 2009 was $68.9 billion. Approach: The objective of this review was to examine the effectiveness of emerging pharmacotherapy’s in patients with acute (≤2 weeks), sub-acute (2-12 weeks) and chronic (≥12 weeks) stroke studied in Randomized … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandomized Clinical Stroke Trials In 2008Meheroz H. RabadiProblem statement: Stroke ranks as the third leading cause of death and the leading cause of serious, long-term disability; estimated direct and indirect cost of stroke for 2009 was $68.9 billion. Approach: The objective of this review was to examine the effectiveness of emerging pharmacotherapies in patients with acute (≤2 weeks), sub-acute (2-12 weeks) and chronic (≥12 weeks) stroke studied … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 8,006 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Case of Refractory Salmonella Spondylodiscitis in an Immunocompetent Patient Treated Via an Extracavitary Approach, Corpectomy and Placement of Expandable CageKimon Bekelis, Oren Gottfried, Zyia L. Gokaslan et al.Problem statement: Salmonella spondylodiscitis is a rare condition that is more prevalent in patients with sickle cell disease or immunosuppression. However, it can also be found in immunocompetent patients. It usually responds well to proper antibiotics. However, surgery is rarely indicated when the infection is refractory to antibiotics, the spine is destabilized or there is an epidural component that is … …American Journal of Infectious Diseases, Vol. 6, Issue 2 · 30 Jun 2010 · 7,535 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Cardiolipin Antibody in Acute Myocardial InfarctionAbdolreza Sotoodeh Jahromi, Mohammad Shojaie, Samira Dana, Abdoulhossain MadaniProblem statement: Myocardial infarction is the combined result of environmental and personal factors. Data concerning the relation between anti-Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anticardiolipin antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study of Anticardiolipin antibody in Acute Myocardial Infarction … …American Journal of Immunology, Vol. 6, Issue 1 · 31 Mar 2010 · 7,829 accessesView PDFCite
Research ArticleOpen accessIn the abstractFoxp3-Mediated Immunity of Human Pancreatic Cancer Cell Line PANC-1Renxi Wang, Gencheng Han, Jianan Wang et al.Problem statement: More and more evidences have shown that human cancer cells can express Foxp3, the regulatory T cell-associated transcription factor. The role of Foxp3 in human cancer cells is still unclear. We detected Foxp3 expression in human pancreatic cancer cell line PANC-1. SiRNA assays showed that Foxp3 expression suppressed the expression of TGF-β and IL-10 which could induce immune … …American Journal of Immunology, Vol. 5, Issue 4 · 11 Jan 2010 · 7,367 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Efficacy of Karkadeh Tea in Controlling Post-Prandial Blood Glucose LevelsAdrian Paul Harrison, Ross Gordon Cooper, Moustafa Ahmed Suliman, Usama AlAlamiProblem statement: Increasing interest from the general public to use herbal remedies, exposes a considerable need to document ancient medical practices, as well as to investigate the efficacy of “ancient” compounds currently reputed to have medicinal benefits for such diseases as diabetes and obesity. Approach: In order to investigate the efficacy of “karkadeh” Roselle-Hibiscus sabdariffa tea as a means of … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 9,435 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Changes in Wistar Rats on Oral Doses of Mistletoe (Loranthus micranthus)D. O. Edem, I. F. UsohProblem statement: To evaluate the effects of the water extract of the leaves of mistletoe (Loranthus micranthus) (traditionally used antidiabetic and antihypertensive) in male albino Wistar rats. Approach: The animals were divided into 4 groups (n = 6). Water extract of L. micranthus leaves was administered in graded doses of 0, 275, 551 and 827 mg kg-1 body weight (wt) … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 8,547 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation of Mycoplasma pneumoniae Infection with Myocardial InfarctionMorteza Pourahmad, Abdolreza Sotoodeh Jahromy, Mohammad ShojaeiProblem statement: In addition to the major risk factors for atherosclerosis such as high plasma level of low density lipoprotein, low plasma level of high density lipoprotein, cigarette smoking, hypertension and diabetes mellitus, some studies introduce other agents such as Mycoplasma pneumoniae as risk factors for atherodclerosis and coronary artery diseases. Aim of this study was to clarify the risk … …American Journal of Immunology, Vol. 5, Issue 3 · 30 Sep 2009 · 7,702 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vivo, Acute, Normo-hypoglycemic, Antihyperglycemic, Insulinotropic Actions of Orally Administered Ethanol Extract of Citrullus colocynthis (L.) Schrab PulpMahmoud Al-Khateeb, Mohammad Dallak, Fahaid Al-Hashem et al.Problem statement: Citrullus colocynthis (L.) Schrab (cucurbitaceae family) (Handal) is a fruit commonly known as bitter apple or bitter cucumber. Traditionally, Citrullus colocynthis has been used for the treatment of diabetes. In particular, the acute effect and rout of administration of ethanol extract of the seedless pulp in vivo remains untested. We investigated the effect of different routs of administration … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,316 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,579 accessesView PDFCite