Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

158 articles for “mice”
Set a search alert
Also matching:3 authors
Research ArticleOpen accessIn the abstractProtection against Lipopolysaccharide-induced Death by An Anti-Interleukin-6 Monoclonal AntibodyBailin Liang, Debra Gardner, Don Griswold, Xiao-yu R. SongSepticemia is frequently associated with serious complications and high mortality despite recent advances in treatment with antibacterial agents. Infectious organisms or their soluble products initiate septic shock through a complex cytokine cascade. Lipopolysaccharide (LPS) induced excessive production of inflammatory cytokines is regarded as a model of septic shock. Experiments of LPS-induced excessive cytokine production were conducted in Balb/c mice for … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 6,856 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntitussive Activity Directed Isolation of Compounds from Onosma hispidumShahina Naz, Rafeeq A. Khan, Rahmanullah Siddiqi, Syed A. SayeedThe chemical investigation of the ethanolic extract of the root bark of Onosma hispidum following antitussive activity directed isolation led to the isolation of 4-hydroxy-3-methoxy cinnamic acid (mCA) and 4-hydroxy-3-methoxy benzoic acid (mBA) which have been reported for the first time in this species. Antitussive activity of the compounds was evaluated by reduction in frequency of cough induced by SO2 … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,322 accessesView PDFCite
Research ArticleOpen accessIn the abstractPDX-1 and MafA: Key Transcription Factors in PancreasHideaki Kaneto, Takeshi Miyatsuka, Yoshihisa Nakatani, Taka-aki MatsuokaPancreatic and duodenal homeobox factor-1 (PDX-1) plays a crucial role in pancreas development, β-cell differentiation and in maintaining normal β-cell function by regulating several β-cell-related genes including insulin. PDX-1 has potency to induce insulin-producing cells in non β-cells in various tissues such as pancreas and liver and PDX-1-VP16 fusion protein more efficiently induces insulin-producing cells, especially in the presence of … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,389 accessesView PDFCite
Research ArticleOpen accessIn the abstractInteraction of a C-terminal Truncated Hepatitis C Virus Core Protein with Plasmid DNA Vaccine Leads to in vitro Assembly of Heterogeneous Virus-like ParticlesNelson Acosta-Rivero, Joanna Poutou, Alexis Mussachio et al.Recently, it has been shown that HCV core proteins (HCcAg) with C-terminal deletions assemble in vitro into virus-like particles (VLPs) in the presence of structured RNA molecules. Results presented in this work showed that a truncated HCcAg variant covering the first 120 aa (HCcAg.120) with a 32 aa N-terminal fusion peptide (6xHistag-XpressTMepitope) interacts with plasmid DNA vaccine. Interestingly, the buoyant … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,754 accessesView PDFCite
Research ArticleOpen accessIn the abstractEssential Role of PKCδ in Apoptosis Induction of Mouse ThymocytesC. Lutz-Nicoladoni, T. Letschka, M. Leitges et al.The family of protein kinases C (PKCs) has been implicated in signal transmission leading to apoptosis induction and/or survival. These effects are cell type and tissue dependent. Numerous studies employing phorbol ester, a pleiotropic PKC activator, strongly implicated PKC in apoptosis induction of thymocytes. However, phorbol esters activate both, the conventional PKCs (PKCα, β, γ) as well as the novel … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 7,135 accessesView PDFCite
Literature ReviewOpen accessIn the abstractOptimizing the Surface-Active Performances of Cat-Anionic Mixtures: A Short ReviewCamillo A. La MesaMixtures of oppositely charged surfactants are used for applications requiring extensive foaming. This holds true for cat-anionic systems. Their bulk behavior is known in detail, when surface, or interface, properties do not attract the same attention. The thermodynamic features of such systems and the strategies interrelating the behavior in bulk to that at surfaces are outlined. Such systems are strongly … …American Journal of Engineering and Applied Sciences, Vol. 16, Issue 4 · 4 Nov 2023 · 4,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractRegeneration of Lyes for Cleaning-In-Place (CIP) Processes in Dairies: Comparison of Recycled Potash and Soda Solutions Cleaning PropertiesMarie Furic, Anne Elain, Walid Blel, Olivier SireThe regeneration of lyes for their integration in the dairy CIP was investigated applying an original process combining adsorption/coagulation and flocculation operations. Solutions of potassium hydroxide (KOH) and caustic soda (NaOH) soiled with 1% (v/v) of whole milk were submitted up to twenty successive regeneration cycles. The multiple recycling of the regenerated solutions was found to modify their physicochemical characteristics … …American Journal of Applied Sciences, Vol. 12, Issue 5 · 6 Jul 2015 · 6,624 accessesView PDFCite
Research ArticleOpen accessIn the abstractNanocrystalline Powders of Alkaline-Earth Phosphates as Precursors for BioceramicsParhi Purnendu, A. Ramanan, Alok R. RayBone is a nanocomposite made of calcium phosphates and collagen. Collagen has a typical fibrous structure, with diameter ranging from 100 nm to 2 μm. It is suggested that calcium hydroxyapatite, Ca10(PO4)6(OH)2 in the size range 5-50 nm embedded in the collagen framework provides mechanical strength to bone. Among calcium phosphates, apatites are found to be the most suitable for … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,543 accessesView PDFCite