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168 results for “Oxidative Stress”
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Research ArticleOpen accessIn the abstractAttenuated Superoxide Dismutase Induction in Retinal Cells in Response to Intermittent High Versus Continuous High GlucoseMichael A. Ihnat, Ronald C. Kaltreider, Jessica E. Thorpe et al.High glucose, particularly in oscillating conditions, produces an increase in oxidative stress and has been shown to result in an increase in diabetic complications, retinopathy in particular. The hypothesis of this work was that chronic exposure to intermittent high glucose results in an attenuated induction of an antioxidant response as compared to continuous high glucose exposure in isolated retinal cells … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 1 · 31 Mar 2007 · 7,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractSpirulina protects against cadmium-induced hepatotoxicity in ratsAmr Amin, Alaaeldin A. Hamza, Sayel Daoud, Waleed HamzaCadmium (Cd) is an environmental and industrial cumulative pollutant that most affects many organs specially the liver. The protective effect of Spirulina, filamentous blue green algae, on Cd – induced oxidative stress and hepatotoxicity was evaluated in male rats. Oral administration of water extract of Spirulina for seven days followed by an acute toxic dose of Cd (3.5 mg kg … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 2 · 30 Jun 2006 · 11,537 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Phenolic Content and Antioxidant Properties of Selected Cowpea Varieties Tested in Bovine Peripheral BloodSarah Adjei-Fremah, Louis EN Jackai, Mulumebet WorkuCowpea is an important grain legume with a dual purpose function as a food and feed resource. Cowpea contains phenolic compounds that are beneficial to human and animal health. We evaluated the phenolic content, condensed tannin content and antioxidant capacities of methanol extracts of seed and leaf of seven varieties commonly used in food and animal feed. The total phenolic … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 4 · 19 Dec 2015 · 7,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Humic Acid on the Content of Trace Element in MitochondriaDaniel Žatko, Janka Vašková, Ladislav Vaško, Peter PatlevičBased on our previous in vitro studies which pointed to the antioxidant properties of humic acids especially concerning radical scavenging activities and ability to maintain the redox system in the cell, an addition of 0.6% humic acid into the diet of farm chicken for 42 days was evaluated. The administration of humic acids have a positive effect on the antioxidant … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 29 Jan 2015 · 7,988 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory, Analgesic and Antioxidant Activities of Allophylus Cobbe LeavesPreeti Jain, Md. Selim Hossain, Kaniz Fatema et al.Allophylus cobbe L. Raeuschel (Family-Sapindaceae) is a medicinal plant used traditionally for the treatment of various health risks like pain, inflammation, ulcers and wounds in Bangladesh. This study determined the polyphenolic compounds and evaluated the analgesic, anti-inflammatory and antioxidant effects of the ethanol extract of Allophylus cobbe leaves. High Performance Liquid Chromatography (HPLC) analysis was used to determine the polyphenolic … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 27 Jan 2015 · 8,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE EFFECTS OF ORAL ADMINISTRATION OF DIFFERENT DOSES OF HYDROALCOHOLIC EXTRACT OF SILYMARIN ON STATUS OF SERUM TRACE ELEMENTSJ. Sajedianfard, S. Nazifi, H. A. ShamsaeiIn this research, the effect of oral administration of different doses of hydroalcoholic extract of silymarin on the status of trace elements with antioxidant properties (Se, Cu, Zn, Mn and Fe) was studied. Fifty male rats were randomly used in five groups including healthy control group (treated by saline), diabetic control group (treated by saline) and three diabetic groups that … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 3 · 24 Oct 2014 · 6,646 accessesView PDFCite
Research ArticleOpen accessIn the abstractAMELIORATIVE EFFECT OF HIBISCUS SABDARIFFA LINN ON SUBCHRONIC CHLORPYRIFOS-INDUCED ALTERATIONS IN SEX AND THYROID HORMONES IN MALE WISTAR RATSShittu Muftau, Olatunji Omobolanle Aisha, Suleiman Folorunsho Ambali et al.Studies have shown that Chlorpyrifos (CPF), an Organophosphate (OP) insecticide alters both sex and thyroid hormones. Apart from inhibiting Acetylcholinesterase (AChE) activity, CPF has been shown to cause oxidative stress. The antioxidant potentials of many flavonoid-containing plants are increasingly being exploited in the therapy of many infectious and non-infectious diseases. Hibiscus Sabdariffa (HS) is one of the most widely used … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 20 Feb 2014 · 9,102 accessesView PDFCite
Research ArticleOpen accessIn the abstractAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,795 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatoprotective Effect of Vitamin EElias Adikwu, Brambaifa NelsonDrugs and some chemical agents are known to induce hepatotoxicity in humans which is of great concern to clinicians. Chemical agents are been screen daily for their hepatoprotective properties. Among these chemical agents is vitamin E which has drawn wide attention due to it reported hepatoprotective property as reported by researchers. This study collected and evaluated reports to ascertain the … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 15 Mar 2013 · 8,006 accessesView PDFCite