146 articles for “Metabolism”

Research ArticleOpen accessIn the abstractThe Effect of Vitamin C on the Metabolic Parameters of Experimental Diabetes MellitusMariam Al-Shamsi, Amr Amin, Ernest AdeghateThe role of vitamin C on diabetes mellitus is unknown. The purpose of this study was to examine the effect of oral administration of vitamin C on some of the metabolic parameters of diabetic rats. Diabetes was induced by intraperitoneal injection of STZ (60 mg kgˉ1 body weight at 12 weeks of age). Vitamin C (10, 50, 100 mg kgˉ1 … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 1 · 31 Mar 2007 · 8,068 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAbnormal Glucose Regulation and Treatment Strategies for Insulin Resistance HIV-Infected PatientsSteven GrinspoonHIV-infected patients receiving highly active antiretroviral therapy often demonstrate abnormalities in glucose regulation, in association with changes in fat distribution[1,2]. In the majority of cases, these abnormalities are best characterized by insulin resistance and impaired glucose tolerance, rather than overt diabetes mellitus and fasting hyperglycemia. Insulin resistance may result from direct effects of antiretroviral therapy, changes in fat distribution or … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,387 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMetabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase InhibitorsMadhu N. Rao, Grace A. Lee, Carl GrunfeldThe use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors for the treatment of HIV infection and AIDS has been associated with multiple abnormalities in glucose and lipid metabolism. Specifically, these abnormalities include insulin resistance, increased triglycerides and increased LDL cholesterol levels. The metabolic disturbances are due to a combination of factors, including the direct effect of medications, restoration to … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,936 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Postgenomic Era: Transcriptomic as the New Paradigm of LifeBruno Giardina, Marcella Renis, Vito Latora, Salvatore MusumeciNow that complete genome sequences are available for a variety of organism, the elucidation of single gene function involved in the metabolism, includes necessarily a better understanding of the cellular responses on all levels of gene products, mRNA, proteins and metabolites. Such knowledge’s growth is essential since the observable properties of living organisms, so called phenotypes, are the results of … …OnLine Journal of Biological Sciences, Vol. 6, Issue 1 · 30 Jun 2006 · 6,822 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNa,K-ATPase α Subunit-like Immunoreactive Proteins in Human Body FluidsJeng-Hsiung F. PengNa,K-ATPase was recently considered a target for breast cancer treatment since its potent inhibitors ouabain and related digitalis compounds that were reported circulating in body fluids before, were found to possess potent anti-breast cancer activity. Based on this finding, it is hypothesized that Na,K-ATPase derivatives could be circulating in the body and potential candidate biomarkers for early disease detection. Western … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,892 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of Dietary Isoleucine Supplementation on the Growth Performance, Carcass Characteristics and Ileal Morphology of Native ChickensCharles Venirius Lisnahan, Oktovianus Rafael Nahak, Lukas PardosiThe roles of isoleucine in the protein synthesis, metabolisms, and growth of chicken have been widely reported. However, its effect on native chicken has not been previously reported. In this work, we reported the effects of dietary isoleucine supplementation on growth performance, carcass characteristics, and ileal morphology in native chickens during the grower phase (6-12 weeks). Two hundred native chickens … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 21 Jun 2025 · 2,940 accessesView PDF Cite