Research ArticleOpen accessAll words, across the recordMechanisms of Anti-Cancer Effects of Vernonia amygdalina Leaf ExtractUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Vernonia amygdalina (V. amygdalina) has been shown to have cancer cell inhibition and cytotoxic effects. Approach: This study discusses the multi-faceted and multi-linked mechanisms by which cancer tissue inhibition and destruction is achieved by V. amygdalina leaf extract and powder (subsequently called V. amygdalina Extract). Cancer cell inhibition by V. amygdalina is suggested to occur through inhibition of … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 26 Oct 2011 · 9,090 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordFormulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery SystemC. D. Licy, K. Premalatha, Annie Shirwaikar, Arun ShirwaikarProblem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldwide have chronic hepatitis B. This is due to problems associated with vaccine delivery, stability and cost. Hence the present challenge in Vaccinology is to develop safer, cheaper and easy-to-deliver forms of … …Current Research in Medicine, Vol. 1, Issue 2 · 30 Oct 2010 · 6,819 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordRetinoids and Opioids: Factors in the Development of HIV-Related Neurological DiseaseWalter Royal, III, Joseph L. BryantNeurological disease occurs frequently in HIV-infected individuals and may occur at even higher rates among infected drug users. Among the potential mechanisms that promote such impairment, retinoid deficiency may have selective effects that could both lead to alterations in immune function and enhanced replication of HIV. Studies are currently underway to examine the possible selective effects of retinoid receptor activation … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 6,764 accessesView PDFCite