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Research ArticleOpen accessIn the abstractAnti-Prm Antibody as an Autoantibody in Dengue Virus InfectionKao-Jean Huang, Yu-Tien Cheng, Yee-Shin Lin et al.We have reported that anti-prM antibody is an enhancing antibody that enhances DV infection of non-Fc receptor bearing cells by dual specificity. We identified the epitope recognized by this anti-prM antibody, M3, which is located at the a.a.53-67of the prM protein nearby the prM/M cleavage junction and these anti-M3 antibodies could be detected in dengue patients sera. Surprisingly, this anti-prM … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,304 accessesView PDFCite
Research ArticleOpen accessIn the abstractFine Needle Aspiration Cytology Evaluation for Classifying Breast Cancer Using Artificial Neural NetworkNor Ashidi Mat Isa, Esugasini Subramaniam, Mohd Yusoff Mashor, Nor Hayati OthmanThirteen cytology of fine needle aspiration image (i.e. cellularity, background information, cohesiveness, significant stromal component, clump thickness, nuclear membrane, bare nuclei, normal nuclei, mitosis, nucleus stain, uniformity of cell, fragility and number of cells in cluster) are evaluated their possibility to be used as input data for artificial neural network in order to classify the breast precancerous cases into four … …American Journal of Applied Sciences, Vol. 4, Issue 12 · 31 Dec 2007 · 7,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractA BI-RADS Based Expert Systems for the Diagnoses of Breast DiseasesUmi Kalthum Ngah, Shalihatun Azlin Aziz, Mohd. Ezane Aziz et al.We proposed an expert system based on the interpretation of mammographic and ultrasound images that may be used by expert and non-expert doctors in the interpretation and classifying of patient cases. The expert system software consists of a mammographic (MAMMEX) and breast ultrasound (SOUNDEX) medical expert systems which may be used to deduce cases according to the Breast Imaging Recording … …American Journal of Applied Sciences, Vol. 4, Issue 11 · 30 Nov 2007 · 7,431 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Identification of Listeria monocytogenes in Processed Meat by a Combined Cultural-molecular MethodAngela Ingianni, Marta Quartuccio, Maria Antonietta Madeddu et al.The isolation and identification of Listeria monocytogenes in processed meat samples by a combined cultural-molecular method is described. It allows the identification of Listeria strains by means of a hybridization technique with a specific DNA probe directed to the listerial internalin gene. The specificity of this method was found to be 100% and sensitivity was as low as 1 CFU/2.5 … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 7,252 accessesView PDFCite
Research ArticleOpen accessIn the abstractRecent Advances in the Synthesis of Artificial Antigen and Its Application in the Detection of Pesticide ResidueTong Dewen, Hesheng Yang, Wang JinyiRecent advances in the research of artificial antigen have shown that artificial antigens can be valuable approach for the treatment of some diseases as well as the detection of pesticide residues. By directly/indirectly coupling hapten to an appropriated carrier (macromolecule), artificial antigen can induce animals to produce hapten-specific antibody. Based on this principle, various vaccines have been developed. More impotently, … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 7,614 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Acute-phase Reactants, Immunologic Markers and other Clinical and Laboratory Parameters in Patients with Pneumonia and Non-pneumonic Lower Respiratory Tract InfectionsJulio Collazos, María del Mar Martínez, Fernando IzquierdoMore efficacious tools to distinguish pneumonia from other acute lower respiratory tract infections (OALRTI) in facilities where radiologic studies are not easily or rapidly available are desirable to select the patients who should undergo chest radiographs, to avoid unnecessary visits to the emergency wards of hospitals and to optimize health resources. To this end we analyzed the relevance of many … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,083 accessesView PDFCite
Research ArticleOpen accessIn the abstractResearch Note: Predicting MRSA Colonization of the Hospitalized Patient on AdmissionRocco J. Perla, Gail E. Cormier, Eric L. Knutson et al.The primary aim of this brief and exploratory study was to examine the ability of two Infection Control Practitioners in a medium size community hospital to effectively predict the MRSA colonization status of patients on admission compared to a standard MRSA screen in real time using only their clinical judgment and review of selected hospital documents. Sensitivity and specificity results … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,316 accessesView PDFCite
Research ArticleOpen accessIn the abstractClozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitroAvril Pereira, Brian DeanTreatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, toxicity may be accounted for by direct action of parent drug or one of its stable metabolites on bone marrow stroma given importance of these cells to neutrophil maturation. Effects of clozapine, N-desmethylclozapine and clozapine N-oxide on … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,109 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Murine Charged Multivesicular Body Protein 2A, CHMP2A Interacts with the 5' and 3' Terminal Regions of Dengue Virus Complementary Minus-strand RNASuchita Chaudhry, Sathyamangalam Swaminathan, Navin KhannaDengue (DEN) viruses, of which there are four distinct serotypes (DEN-1, -2, -3 and –4), belong to the Flaviviridae family. Their ‘plus’ sense RNA genomes contain Non-Translated Regions (NTRs) at their 5’ and 3’ ends. Replication of viral genomic RNA, which takes place in close association with host cell membranes, involves the initial synthesis of the complementary minus sense RNA … …American Journal of Infectious Diseases, Vol. 2, Issue 1 · 31 Mar 2006 · 7,314 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntroduction of Three Complementary Technologies into Clinical Medicine: Development of New Diagnostic and Prognostic ParametersGernot P. Tilz, Marco Wiltgen, Ulrike Demel et al.Molecular medicine leads us to understand some diseases at the molecular level. Examples are the analysis of immune complexes and receptor - anti receptor compounds used in clinical medicine. Structural changes of some serum proteins occur in inflammation, neoplasie and autoimmunity. The detection and analysis of such structural modifications may offer a new field for the diagnosis, prognosis and therapy … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,956 accessesView PDFCite