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131 results for “pathogenic”
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Research ArticleOpen accessIn the abstractGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,423 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico Assessment of the Arg85Trp Glucokinase Mutation EffectsFaiza Bouldjennet, Souhila Bouaziz-Terrachet, Malha Azzouz, Rachida RaacheMaturity Onset Diabetes of the Young (MODY) is a heterogeneous group of autosomal dominantly inherited, young-onset β-cell disorders that account for approximately 2% of non-insulin-dependent diabetics in Europe. MODY2 or GCK-MODY is caused by inactivating heterozygous mutations in the glucokinase. Linkage of MODY to the Arg85Trp GCK mutation, among Algerian diabetic patients has been established in our previous research. The … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,808 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of Klebsiella Pneumoniae as a Nosocomial Pathogen and ESBL Producing Strains in IranFariba Akrami, Amirmorteza Ebrahimzadeh Namvar, Iman Vazife SirzariKlebsiella pneumoniae is one of the most important human bacterial pathogens with an extensive range of community and hospital acquired infections that may lead to morbidity and mortality. Evaluating the prevalence and epidemic sources of infections and the pathogenicity mechanism of bacteria can be investigated by various typing methods. The emergence of multi-drug resistant strains and extended-spectrum ß-lactamase (ESBL) producing … …American Journal of Infectious Diseases, Vol. 15, Issue 1 · 11 Mar 2019 · 7,890 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation, Identification and Genomic Analysis of Plesiomonas shigelloides Isolated from Diseased Percocypris pingi (Tchang, 1930)Lei Pan, Shuiyi Liu, Xuwei Cheng et al.Recently, the outbreak of a serious infectious disease of unknown etiology was noted in Percocypris pingi (Tchang, 1930) farms in Yunnan province. Due to currently limited information, we aimed to identify the pathogen isolates, determine the susceptibility of the isolates, evaluate the pathogenicity and analyze the genome of the representative strain. Ten strains of Gram-negative rods were isolated from diseased … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 22 Dec 2017 · 8,836 accessesView PDFCite
Research ArticleOpen accessIn the abstractControl of Subterranean Termite Coptotermes Curvignathus (Isoptera: Rhinotermitidae) by Entomopathogen Metarhizium Anisopliae Var. Anisopliae Cultured in Liquid State FermentationVei-Ting Nyam, Choon-Fah J. Bong, Jie-Hung P. KingSolid state fermentation has been used for mass production of Metarhizium anisopliae many years ago. However, solid state fermentation was time consuming, costly and unable to produce in large amount. We examined the suitability of liquid state fermentation to mass produce M. anisopliae and the effect of culture medium on fungal pathogenicity. Three different liquid medium selected for this study … …American Journal of Agricultural and Biological Sciences, Vol. 10, Issue 1 · 6 Apr 2015 · 7,534 accessesView PDFCite
EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,166 accessesView PDFCite
Research ArticleOpen accessIn the abstractASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,073 accessesView PDFCite
Research ArticleOpen accessIn the abstractIDENTIFICATION OF THE BACTERIUM TOMATO STEM CANKERGoner A. ShakerDiseased tomato samples were collected from green house was evaluated for isolation, pathogenicity and biochemical tests. The symptoms of the infected tomato plants were as sudden wilting after curled on leaves and necrotic streak regions developed at the crown and base of the stem and the cavities deepen and expand up and down, brown discoloration and necrosis occurring on xylem … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 20 Feb 2014 · 7,469 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Characteristics of P. xylostella Granulovirus and Effects on Its Larval Host Diamondback Moth Plutella xylostella L. (Lepidoptera, Plutellidae)A. Dezianian, A. S. Sajap, W. H. Lau et al.Problem Statement: Diamondback moth, Plutella xylostella L. (Lepidoptera, Plutellidae) is the most destructive insect pest of cruciferous plants throughout the world which become resistant to wide range of chemical pesticides. PxGV is known as an effective factor on diamondback moth larval mortality. Approach: Some morphological characteristics, viral DNA isolation and Restriction Endonuclease (REN) analysis of P. xylostella granulovirus and its … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 1 · 31 Mar 2010 · 10,157 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe First Report of the Occurrence of Anthracnose Disease Caused by Colletotrichum gloeosporioides (Penz.) Penz. & Sacc. on Dragon Fruit (Hylocereus spp.) in Peninsular MalaysiaMasanto Masyahit, Kamaruzaman Sijam, Yahya Awang, Mohd Ghazali Mohd SatarProblem statement: The increasing of dragon fruit (Hylocereus spp.) plantations in Malaysia enhances the researches on this crop, particularly focusing on its physico-chemical characteristics, great potential health benefits and nutritional value. However, its scientific report of disease is still lacking, primarily on anthracnose disease. This study was then conducted to investigate the distribution of anthracnose disease on dragon fruit and … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 11,824 accessesView PDFCite