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Research ArticleOpen accessIn the abstractThe Role of Receptor Activator of Nuclear Factor Kappa B (RANK) and Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) in Osteoporosis Risk: Gene Polymorphism and Soluble RANKL Level in Indonesia Post-Menopausal WomenLuluk Yunaini, Dwi Anita Suryandari, Linda Kusdhany et al.Hormonal changes in postmenopausal women may increase osteoclastogenesis that can lead to increased risk of osteoporosis. Receptor Activator of Nuclear factor Kappa B (RANK) and Receptor Activator of Nuclear factor Kappa B Ligand (RANKL) have an important role in osteoclastogenesis that involve in the regulation of bone resorption. In this study, we analyzed the Single Nucleotide Polymorphism (SNPs) within the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 27 Sep 2018 · 8,180 accessesView PDFCite
Research ArticleOpen accessIn the abstractGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,423 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship of Scrotal Circumference with Spermatozoa Production in Various Breed of Indonesian Local BullsTrinil Susilawati, Nisa’us Sholikah, Sri Wahjuningsih et al.Bulls for artificial insemination must qualify as a superior bull that has good genetic quality and semen production. Therefore, the selection process for bulls must be carried out accurately. The study aims to determine the relationship between scrotal circumference with semen production in the Ongole crossbred, Bali, Madura and Brahman bulls. The research materials were four breeds of bull Ongole … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 2 · 28 Apr 2020 · 7,707 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Effective and Viable DNA Extraction Protocol for FFPE Tissues and its Effect on Downstream Molecular ApplicationSai Sushmitha Kontham, Charles Emmanuel Jebaraj Walter, Manjula Raju et al.Archival Formalin-Fixed Paraffin-Embedded (FFPE) tissues are a readily available source of DNA for retrospective studies including genetic predisposition. FFPE tissues present significant challenges for extraction of pure genomic DNA in adequate amounts due to the harsh fixation conditions and long-term storage associated with samples. The aim of the study is to propose a simple, in-expensive, viable protocol for the extraction … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 24 Mar 2020 · 7,374 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Approach to Identify Gobioid Fishes, “Nike” and “Hundala” (Local Name), from Gorontalo Waters, IndonesiaAbdul Hafidz Olii, Femy M. Sahami, Sri Nuryatin Hamzah, Nuralim PasisingiData of the species scientific name is required to study biodiversity and conservation of local fish species. Nike and hundala are the local names for fish found in Gorontalo whose scientific names are unknown and recognized by local people as two different species of fish. This study aims to identify the genetic and species of nike and hundala fish. Nike … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 11 Feb 2019 · 8,506 accessesView PDFCite
Research ArticleOpen accessIn the abstractFatigue Life Prediction of Screw Blade in Screw Sand Washing Machine under Random Load with Gauss DistributionJie Gong, Yun-Fei Fu, Wen Xia et al.The purpose of this study is to present a new method for estimating the fatigue life of the screw blade in the screw sand washing machine. To ensure the accuracy of numerical simulation, the loading area and the value of load are determined by means of the theoretical analysis. To ascertain the location of the stress peak and stress range, … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 22 Dec 2016 · 8,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Characterization of Vaccine-Derived Mutants of Avian Metapneumoviruses Isolated from Turkeys in EgyptAbdel-Satar Arafa, Wessam Mady, Ahmed Hussein et al.Avian metapneumovirus (aMPV) causes acute respiratory infection in turkeys with sudden onset and rapid spread in the infected flocks. Vaccinated flocks frequently showed clinical signs typical like the non-vaccinated flocks in Egypt, this situation suggests a virulent vaccine virus was circulating in the field. Oropharyngeal and nasal sinus swabs were collected from 100 turkeys from 10 commercial farms with mild … …Current Research in Virology, Vol. 4, Issue 1 · 12 Aug 2015 · 12,748 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy on Follicle Stimulating Hormone Receptor Gene Polymorphisms in South Indian Women with Polycystic Ovarian SyndromeHimavanth Reddy Kambalachenu, Solomon Franklin Durairaj Paul, Sanjeeva Reddy Nellepalli, Perumal VenkatachalamPolycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder of women in their reproductive ages. Though PCOS is a complex, heterogeneous disorder, but there is strong evidence for its genetic predisposition. The aim was to study the association of Follicle Stimulating Hormone Receptor (FSHR) gene polymorphisms rs1394205, rs6165 and rs6166 in south Indian women with PCOS. The present case … …Current Research in Medicine, Vol. 4, Issue 2 · 4 Sep 2013 · 12,695 accessesView PDFCite
Research ArticleOpen accessIn the abstractTaxonomically Clustering Organisms Based on the Profiles of Gene Sequences Using PCAE. Ramaraj, M. PunithavalliThe biological implications of bioinformatics can already be seen in various implementations. Biological taxonomy may seem like a simple science in which the biologists merely observe similarities among organisms and construct classifications according to those similarities[1], but it is not so simple. By applying data mining techniques on gene sequence database we can cluster the data to find interesting similarities … …Journal of Computer Science, Vol. 2, Issue 3 · 31 Mar 2006 · 6,746 accessesView PDFCite
Review ArticleOpen accessIn the abstractHealthcare Driven by Big Data AnalyticsCheryl Ann Alexander, Lidong WangText messages and social network posts are often included in big data and are frequently invaluable sources of health data. When machine learning or data mining is used, it is important to perform an automatic process for integrating all available and related health data. Artificial Neural Network (ANN) is one of the machine learning methods flexible in using algorithms to … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 3 · 28 Sep 2018 · 7,398 accessesView PDFCite