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130 articles for “NER”
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Research ArticleOpen accessIn the abstractHIV-1 Infection and Central Monoamine NeurotransmittersAdarsh M. Kumar, J. B. Fernandez, Irina Borodowsky et al.Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine neurotransmitters systems, such as dopamine (DA), and 5-hydroxytryptamine (5-HT, serotonin), resulting in … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,491 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Canadian Regulations and Remediation Methods for Diesel Oil Contaminated SoilsD. G. Rushton, A E. Ghaly, K. MartinellDiesel fuel released into the environment can contaminate ground water, degrade potable water supplies and cause the collapse of fisheries. They are toxic to both animals and humans and can affect the liver, lungs, kidneys, and nervous system leading to cancer as well as immunological and reproductive effects. The objectives of this study were to review current Canadian regulations pertaining … …American Journal of Applied Sciences, Vol. 4, Issue 7 · 31 Jul 2007 · 8,758 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign of CHWHG Type Low Frequency Magnetic Fields GeneratorBo Cheng, Ahmed N. Abdalla, Xi Huang et al.Highly considering the invariability of magnetic field strength in the Magnetic Field Generators, which used to stimulate rat's nerve cell, surely improve the stimulation performance outcome. A new technique to get an invariable magnetic field strength within Magnetic Field Generator has been proposed, Furthermore it had implemented on microcontroller-based system providing an Alternating Magnetic Field Generator (AMFG) with a high … …Journal of Computer Science, Vol. 3, Issue 2 · 28 Feb 2007 · 6,965 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Dysfunction among HIV Infected Drug AbusersRamani S. Durvasula, Charles H. HinkinHuman immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction and memory impairment (characterized by intact … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractOpiates Upregulate Adhesion Molecule Expression in Brain MicroVascular Endothelial Cells (BMVEC): Implications for Altered Blood Brain Barrier (BBB) PermeabilityMadhavan P.N. Nair, Supriya D. Mahajan, Jessica L. ReynoldsThe blood-brain barrier (BBB) is an intricate cellular system composed of vascular endothelial cells and perivascular astrocytes that restrict the passage of immunocompetent cells into the central nervous system (CNS). Expression of the adhesion molecules, intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on brain microvascular endothelial cells (BMVEC) and their interaction with human immunodeficiency virus (HIV-1) … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,610 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Changing Pathology of NeuroAIDS Associated with Drug Abuse in the Era of HAARTE Bell Jeanne, C. Anthony Iain, Simmonds PeterCompliance with highly active antiretroviral therapy (HAART) arrests HIV induced immune collapse and reduces the prevalence of severe central nervous system (CNS) complications, including HIV associated dementia and encephalitis. However minor cognitive disorders remain common and recent autopsy studies have demonstrated the presence of subtle neuropathological abnormalities in HAART treated individuals, including persistent neuroinflammation and enhanced deposition in the brain … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,872 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntagonism Between Chlorpyrifos and Flaxedil in Toad and Earthworm Neuromuscular TransmissionYong-Chiang Chang, Amauri B. Bartoszeck, Samir A. Madeira, Charles I. AbramsonThe cholinesterase inhibition effect of chlorpyrifos, a commercial insecticide, was tested by its antagonism to the acetylcholine inhibition effect of flaxedil in 30 isolated nerve-sartorius muscle preparations of the toad, compared with its antagonism in 30 isolated nerve cord-body wall muscle preparations of the earthworm. Inhibition and facilitation in this antagonism were measured by changes in depolarizing rate of toad … …American Journal of Environmental Sciences, Vol. 2, Issue 2 · 30 Jun 2006 · 6,389 accessesView PDFCite
Research ArticleOpen accessIn the abstractγ-Aninobutyric acid (GABA) suppresses antigen-specific immune responses in ovalbumin γ(OVA)-immunized BALB/c miceTohru Sakai, Hiroko Okada, Mitsuo Kise et al.γ-Aminobutruic acid (GABA) is known to be a ubiquitous inhibitory neurotransmitter in the central nervous system. Furthermore, recent studies have shown that GABA modulates cardiovascular and respiratory functions. In this study, we examined the effect of GABA on antigen (Ag)-specific immune responses and elucidated the mechanisms underlying those effects in ovalbumin (OVA)-immunized BALB/c mice. OVA-specific proliferative responses were decreased in … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,501 accessesView PDFCite
Research ArticleOpen accessIn the abstractElectro-diagnostic and Clinical Changes of Peripheral Neuropathies in Bam Earthquake VictimsNaser Zangiabadi, Mohammad Naeem AhrariTo examine and diagnose patients who injured in Bam earthquake at 5:26:52 Am (local time) on Friday, December 26, 2003 with traumatic peripheral neuropathies then treat and follow up. A longitudinal study was deigned. 159 patients with traumatic neuropathies were selected at the first stage of study. After six months follow up only 39 patients satisfied to enter the study. … …American Journal of Environmental Sciences, Vol. 1, Issue 3 · 30 Sep 2005 · 6,712 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Cellular Responses of Purine Nucleoside-mediated Protection of Hypoxia-induced Injuries of Neuronal PC12 CellsBettina Tomaselli, Valerie Podhraski, Günther Böck, Gabriele Baier-BitterlichHypoxia in brain may lead to cell death by apoptosis and necrosis. In parallel adenosine, a powerful endogenous neuroprotectant is formed. We wanted to investigate the effect of adenosine and its purine nucleoside relatives, inosine and guanosine on early cellular responses to hypoxia. O2-sensitive neuronal PC12-cells were subjected to chemical hypoxia induced with rotenone, an inhibitor of mitochondrial complex I. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,853 accessesView PDFCite