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Research ArticleOpen accessIn the abstractIn silico Modeling of α1A-Adrenoceptor: Interaction of its Normal and Mutated Active Sites with Noradrenaline as well as its Agonist and AntagonistRamchandran Vijayan, Naidu Subbarao, Birendra Nath MallickNoradrenaline, like most other neurotransmitters, acts through various adrenoceptor subtypes. The structure and active site of adrenoceptors for the binding of noradrenaline were unknown, however, such information are crucial for understanding the molecular mechanism of action of neurotransmitters, including noradrenaline, in health and disease as well as for drug designing. In this in silico study, we modeled the α1A-adrenoceptor; a … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,140 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Heat Shock Transcription Factor Family in Entamoeba histolyticaConsuelo G. García, Ma. De la Luz Macias Argüelles, D. Guillermo P Ishiwara et al.The HSTF is a master molecule involved in the transcriptional control of several genes during different types of stress. This transcription factor is a very conserved protein identified in different organisms from bacterial to human. Entamoeba histolytica is the protozoan responsible for the human amoebiasis. This parasite is exposed to different kind of stress as changes in the pH, temperature, … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,182 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression, Purification and Activity Assay of Two New Recombinant Antagonists of Fibrinogen ReceptorJianbo Yang, Jia Yao, Kun Yang et al.The gene sequence of Decorsin which is extracted from a kind of North American leeches was synthesized. Two recombinant proteins, Annexin V plus Decorsin (AnnV-D39) and Annexin V plus the carboxyl terminal 27 amino acid residues of Decorsin(AnnV-D27), were constructed. And a 10 amino acids linker peptide of GGGGSGGGGS was inserted between Annexin V and Decorsin in AnnV-D39. Using pET-28(a+) … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,913 accessesView PDFCite
Research ArticleOpen accessIn the abstractBinding of the scutellarin to albumin using tryptophan fluorescence quenching, CD and FT-IR spectraJianniao Tian, Jiaqin Liu, Zhide Hu, Xingguo ChenThe binding of scutellarin with bovine serum albumin (BSA) was investigated at three temperatures, 296k, 310K, and 318K, by the fluorescence, circular dichroism (CD) and fourier transform infrared spectroscopy (FT-IR) at pH 7.40. The binding parameters were determined by Stern-Volmer equation. The thermodynamic parameters were calculated according to the dependence of enthalpy change on the temperature as follows:ΔH0 and ΔS0 … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 13,643 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial Effect of Untreated and Treated (Decolorized) Dyes by Agricultural WastesSibel Kahraman, Pelin YalcinToxicity (antibacterial effect) of untreated and treated (decolorized) dyes on a soil bacterium, Pseudomonas aeruginosa was determined. Low cost and easily available two agricultural residues (cotton stalk and apricot seed) as biosorbents were used to remove Astrazone Black and Astrazone Yellow from aqueous solution. The removal of these dyes with agricultural wastes reduced the toxic effect on P. aeruginosa. This … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 1 · 31 Mar 2005 · 7,260 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplication of Polyelectrolyte in Turbidity Removal from Surface WaterA. H. Mahvi, M. RazaviOne of the most important treatment processes in surface water treatment plants is coagulation. Surface waters such as rivers and lakes contain suspended particles and turbidity. With the aid of coagulants, and by flocculation process, followed by sedimentation and filtration, these impurities can be removed from raw waters these days, besides conventional chemicals such as Alum and Ferric chloride, polymers … …American Journal of Applied Sciences, Vol. 2, Issue 1 · 31 Jan 2005 · 8,237 accessesView PDFCite