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143 results for “Cell model”
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Research ArticleOpen accessIn the abstractAlterations in Interleukin-1β and Interleukin-6 in Mice Inoculated Through the Oral Routes Using Graded Doses of p. Multocida Type b: 2 and its LipopolysaccharideOmar Suwaidan Ali, Lawan Adamu, Faez Firdaus Jesse Abdullah et al.The gram-negative bacterium Pasteurella multocida serotype B: 2 is an important veterinary and opportunistic human pathogen that causes deplorable welfare problems and colossal economic production losses in bovine and other animal species throughout the world. Pasteurella multocida type B: 2 and its LPS are associated with Haemorrhagic Septicaemia (HS) in mice as animal model. Sixty healthy Balb c mice were … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 1 · 22 Dec 2014 · 7,692 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECT OF ZINC OXIDE NANOPARTICLES ON NEUROBLASTOMA SH-SY5Y CELLSJinghui Zheng, Theresia Schnurr, Kriya Dunlap et al.The Arctic and sub-arctic regions are impacted by the growth of the global nanotechnology industry and the transport of chemicals to the North. New nanotechnology industries, such as neural prothesis, are bringing nanomaterials in direct contact with neurons and glial cells. Nanomaterials have unique chemical and physical properties that may lead to toxicological effects by interfering with normal cellular metabolism. … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 2 · 4 Jul 2014 · 8,488 accessesView PDFCite
Research ArticleOpen accessIn the abstractEXPOSURE TO SWINE HOUSING DUST MODULATES MACROPHAGE MORPHOLOGY AND FUNCTIONRuth J. Pender, Radiah C. Minor, Steven L. Hurley et al.Swine Confinement Facility (SCF) dust consists of a complex mixture of feed grain particles, bacterial components, organic particulates and gases. When these particles are inhaled they deposit along the respiratory tract and mediate respiratory symptoms and disease in swine farmers and facility workers. Macrophages ingest and eliminate microbes and debris under chronic conditions; however, the role of macrophages in agricultural-related … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,606 accessesView PDFCite
Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Arthritic Activity of the Methanolic Leaf Extract of Urtica pilulifera L. on Albino RatsSuha Abudoleh, Ahmad Disi, Eyad Qunaibi, Talal AburjaiProblem statement: Urtica pilulifera (Urticeacae) has been used in folk medicine to alleviate inflammation and arthritis. In this study the anti-arthritic effect of methanolic leaf extract of the plant was evaluated and compared to untreated control as well as ibuprofen-treated groups in a rat model of Complete Freund's Adjuvant (CFA)-induced arthritis. Approach: Arthritis was induced by injecting CFA subcutaneously into … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 14 Jun 2011 · 10,431 accessesView PDFCite
Research ArticleOpen accessIn the abstractGrowth of Bone Marrow Derived Osteoblast-Like Cells into Coral Implant Scaffold: Preliminary Study on Malaysian CoralK. A. AL-SalihiProblem statement: Biomaterial fabrication in Malaysia started as a consequence of the demand for cheaper implant materials. Various biomaterials have been developed utilizing local resources like Malaysian coral. Locally processed Malaysian coral need to be complemented with proper evaluation and testing including toxicology, biocompatibility, mechanical properties, physicochemical characterization and in vivo testing. The present study was carried out to assess … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 6,590 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling, Simulation and Optimization of Steel Sandwich Panels under Blast LoadingSayed M. Soleimani, Nader H. Ghareeb, Nourhan H. ShakerHoneycomb sandwich panels are commonly preferred in structural engineering as a design element meant to protect against blast loading, and this owes primarily to the fact that they are light in weight (due to the voids present) whilst carrying high energy absorption capacities. A widespread surge in acts of terrorism, and the resultant threat posed to structures, presents structural engineers … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 3 · 24 Aug 2018 · 7,858 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanically Stimulated Osteoblast Cells GrowthRaffaella Aversa, Antonio Apicella, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe bones need to be built and then permanently restored to keep them functioning properly. Considering the multiple bone functions, their vitality is essential both to maintain the body and move it and to maintain its health and vigor. When most bones begin to age and have no vital function, the man also begins to age, lose water, minerals, electrolytes, … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 19 Jun 2018 · 7,882 accessesView PDFCite