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105 articles for “Vaccine”
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Research ArticleOpen accessIn the abstractAnti-Platelet and Anti-Endothelial Cell Autoantibodies in Vietnamese Infants and Children with Dengue Hemorrhagic FeverNguyen Thanh Hung, Nguyen Trong Lan, Yee-Shin Lin et al.Dengue hemorrhagic fever (DHF) is a serious public health problem. Increased vascular permeability and thrombocytopenia are the hallmarks of DHF. The mechanisms involved in DHF/Dengue shock syndrome (DSS) pathogenesis is not fully understood. This study gives evidence of the presence of antibodies which cross-reacted with platelets, and endothelial cells in the sera of Vietnamese infants and children with DHF/DSS. The … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,369 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduction of a Soluble Anti-HIV-1 factor (s) with IFN-γ, IL-10, and β-Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic MixtureJosé W. Rodríguez, Nat O. Pagan, Mar C. Ocasio et al.Partial immune restoration may be obtained with highly active antiretroviral therapy (HAART), but specific anti-HIV-1 immune responses do not appear to improve substantially. We have demonstrated that a soluble factor(s) induced by a mixture of inactivated influenza and bacterial vaccines called polyantigenic immunomodulator (PAI), possesses strong immunoregulatory and anti- HIV-1 activities. In the present study, we show that culture fluids … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the abstractRecent Advances in the Synthesis of Artificial Antigen and Its Application in the Detection of Pesticide ResidueTong Dewen, Hesheng Yang, Wang JinyiRecent advances in the research of artificial antigen have shown that artificial antigens can be valuable approach for the treatment of some diseases as well as the detection of pesticide residues. By directly/indirectly coupling hapten to an appropriated carrier (macromolecule), artificial antigen can induce animals to produce hapten-specific antibody. Based on this principle, various vaccines have been developed. More impotently, … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 7,614 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunological Evidence for Peptide-Carbohydrate Mimicry with a Group A Streptococcus Polysaccharide-Mimetic PeptideSilvia Borrelli, Rehana B. Hossany, Susan Findlay, B. Mario PintoThe immunogenicity of a peptide-protein conjugate developed by linking a peptide mimic DRPVPY of the Group A Streptococcus cell-wall polysaccharide (GAS-CWPS), to tetanus toxoid (TT) was examined. BALB/c mice were immunized three times subcutaneously following homologous or heterologous prime/boost strategies at 4- or 6- week intervals in two different experiments. DRPVPY-TT, CWPS-TT, heat-killed, pepsin-treated GAS bacteria (with exposed polysaccharide) and … …American Journal of Immunology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpidemiologic Assessment of the Protective Effects of Smallpox VaccinationHiroshi Nishiura, Isao Arita, Markus Schwehm, Martin EichnerDespite smallpox eradication, the widely discussed possibility of a bioterrorist attack using a variola virus makes it necessary to review the epidemiology of smallpox and the effects of various vaccination schemes. This paper provides a literature review concerning the epidemiologic assessment of the protective effects of smallpox vaccination, with particular emphasis on the statistical and theoretical points of view. Although … …American Journal of Infectious Diseases, Vol. 2, Issue 1 · 31 Mar 2006 · 7,010 accessesView PDFCite