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131 articles for “P3 Bone”
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Review ArticleOpen accessIn the abstractThe Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with AgeManar M. IsmailAML originates from genetic insults of hematopoietic stem and progenitor cells (HSPCs/HSCs) that was identified earlier as leukemia stem cells (LSCs). In quiescent state, trafficking immune cells are crucial for eradication of aberrant clones and obtaining balance between proliferation and apoptosis to maintain HSCs pool. Regulatory T-cells shield the HSCs from the inflammatory reactions by suppressing T- and B- cells. … …American Journal of Immunology, Vol. 13, Issue 4 · 22 Dec 2017 · 7,807 accessesView PDFCite
Research ArticleOpen accessIn the abstractβ-Glucan in AllergiesSima Petr, Vetvicka VaclavMultiple effects of β-glucan are well established. Together with the effects on antibacterial and anticancer immunity, glucan has been shown to stimulate bone marrow cells, lower cholesterol and to protects against stress and some kinds of poisoning. However, despite literally thousands of papers describing biological effects of β-glucan, only limited attention has been focused on the role of β-glucan in … …American Journal of Immunology, Vol. 13, Issue 1 · 30 Mar 2017 · 8,985 accessesView PDFCite
Research ArticleOpen accessIn the abstractNano-Diamond Hybrid Materials for Structural Biomedical ApplicationRaffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuThe development of new diamond based bio-mechanically active hybrid nano-structured scaffolds for cartilage cells tissue engineering are proposed in this study. Innovative tissue engineering biomimetic materials based on hydrogel have shown attractive physical, biological and mechanical properties in several biomedical applications. A highly biocompatible novel hybrid material based on nanodiamonds and hydrophilic poly-(hydroxyl-ethyl-methacrylate) (pHEMA) is proposed. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 1 · 9 Mar 2017 · 9,189 accessesView PDFCite
Research ArticleOpen accessIn the abstractFlexible Stem Trabecular ProsthesesRaffaella Aversa, Florian Ion T. Petrescu, Relly Victoria V. Petrescu, Antonio ApicellaThe complex biomechanics and morphology of the femur proximal epiphysis are presented. This specific region in human femur is characterized by a high flexibility compared to that of other primates, since evolved lighter and longer due to the human verticalposition and more balanced loading. The nature and fine morphology of the femur head and its structural behavior have been investigated. … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 22 Dec 2016 · 7,860 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiofidel FEA Modeling of Customized Hybrid Biological Hip Joint Design Part II: Flexible Stem Trabecular ProsthesesRaffaella Aversa, Florian Ion T. Petrescu, Relly Victoria V. Petrescu, Antonio ApicellaNew biomechanical criteria for the design of biomimetic hip joint prostheses are presented. Biofidel Finite Element Models have been used both to correctly analyze femur physiological and structural behavior and to assess a new design criterion for the development of innovative hybrid biological hip prostheses. Proper identification of isostatic lines and isorigidity regions for the sintered metal trabecular lattices distribution … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 4 · 16 Dec 2016 · 8,616 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysiologic Human Fluids and Swelling Behavior of Hydrophilic Biocompatible Hybrid Ceramo-Polymeric MaterialsAversa Raffaella, Relly Victoria V. Petrescu, Apicella Antonio, Florian Ion T. PetrescuAll synthetic and natural materials to be used in biomedical applications that involve the contact with human body need to be investigated for their physical and chemical modification induced by the human physiological fluids contact and sorption. The development and testing in human physiological equivalent fluids of new hybrid biomaterials are presented. The role of water and its equilibrium modification … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 8 Nov 2016 · 8,393 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,949 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioaccumulation and Tissue Partitioning of Endosulfan by the Red Hybrid TilapiaDwight E. RobinsonThe frequent use of endosulfan in agricultural activity on steep slopes in Jamaica and subsequent contamination of rivers by the residues resulted in a need to assess the levels of bioaccumulation of sub-lethal doses of the insecticide in river fauna using Tilapia fish as a test subject. Bioconcentration of α- and β-endosulfan by the Red Hybrid Tilapia, from 0.0075 mg … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 29 Jun 2015 · 7,063 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Review on Biochemical Mechanism of Fatty Acids Synthesis and Oil Deposition in Brassica and ArabidopsisMukhlesur RahmanOilseeds crops provide edible oil for humans’ diet or oil for industrial purpose. Triacylglycerols (TAG) are the main components in seed oil which is formed by the esterification of fatty acids to glycerol back bone. In plants, fatty acid biosynthesis process initiated in plastid and ended in the endoplasmic reticulum. A series of biochemical steps are involved in TAG formation … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 4 · 17 Jan 2015 · 7,530 accessesView PDFCite
Research ArticleOpen accessIn the abstractMesenchymal Stem Cell Transplantation for Retinal Degenerations and Dystrophies: Present and FutureEmma Ghazaryan, Shurong Wang, Yan Zhang et al.Retinal degenerations are the main causes of irreversible blindness in developed countries. Up to date the main pathological mechanisms of these diseases are not fully understood and consequently there is no complete treatment option for those diseases. In this aspect stem cells have drawn attention of many researchers and health care professionals. Considering ethical issues, safety and facile isolation Mesenchymal … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 28 Nov 2014 · 6,768 accessesView PDFCite