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125 results for “Expression Analysis”
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Research ArticleOpen accessIn the abstractGenomic Distance between Thymidylate Synthase and Dihydrofolate Reductase Genes Does Not Correlate With Phylogenetic Evolution in BacteriaVitor Hugo MoreauProblem statement: Dihydrofolate Reductase (DHFR) and Thymidylate Synthase (TS) exist as bifunctional enzymes coded into unique polypeptide chain in protozoans. Bifunctional DHFR-TS is associated with an increase in the enzymatic activity by channeling the substrate between the active sites. In some bacteria, DHFR and TS genes are neighbors in the genome, whereas in others, they are located millions of base … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,188 accessesView PDFCite
Research ArticleOpen accessIn the abstractHyper-Ag-specific Ab Production in NC/Nga Mice is not associated with Deletion Polymorphism in the Promotor Region of the FcγRIIB GeneTohru Sakai, Mariko Nakamoto, Emi SutoProblem statement: NC/Nga (NC) mice produced high levels of ovalbumin (OVA)-specific IgG, IgG1 and IgG2a. We previously found deletion polymorphisms in the promoter region of fcgr2b in NC mice. To determine whether this mutation causes a hyper-humoral immune response, we generated congenic BALB/c mice carrying the NC-type fcgr2b allele (NC fcgr2b) and analyzed humoral immune response and FcγRIIB on germinal … …American Journal of Immunology, Vol. 5, Issue 3 · 31 Dec 2009 · 7,364 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparison of Bleeding Time and Clotting Time in Different Blood GroupsB. Mahapatra, N. MishraProblem statement: Researchers have demonstrated that epistaxis is more often encountered in patients having blood group O probably due to lower expression of von Willebrand factor. We had taken up this study to find out if there is any definite relationship between the blood groups with the bleeding time and clotting time in our population. Approach: This retrospective study was … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 10,976 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Heat Shock Transcription Factor Family in Entamoeba histolyticaConsuelo G. García, Ma. De la Luz Macias Argüelles, D. Guillermo P Ishiwara et al.The HSTF is a master molecule involved in the transcriptional control of several genes during different types of stress. This transcription factor is a very conserved protein identified in different organisms from bacterial to human. Entamoeba histolytica is the protozoan responsible for the human amoebiasis. This parasite is exposed to different kind of stress as changes in the pH, temperature, … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,182 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Postgenomic Era: Transcriptomic as the New Paradigm of LifeBruno Giardina, Marcella Renis, Vito Latora, Salvatore MusumeciNow that complete genome sequences are available for a variety of organism, the elucidation of single gene function involved in the metabolism, includes necessarily a better understanding of the cellular responses on all levels of gene products, mRNA, proteins and metabolites. Such knowledge’s growth is essential since the observable properties of living organisms, so called phenotypes, are the results of … …OnLine Journal of Biological Sciences, Vol. 6, Issue 1 · 30 Jun 2006 · 6,822 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Murine Charged Multivesicular Body Protein 2A, CHMP2A Interacts with the 5' and 3' Terminal Regions of Dengue Virus Complementary Minus-strand RNASuchita Chaudhry, Sathyamangalam Swaminathan, Navin KhannaDengue (DEN) viruses, of which there are four distinct serotypes (DEN-1, -2, -3 and –4), belong to the Flaviviridae family. Their ‘plus’ sense RNA genomes contain Non-Translated Regions (NTRs) at their 5’ and 3’ ends. Replication of viral genomic RNA, which takes place in close association with host cell membranes, involves the initial synthesis of the complementary minus sense RNA … …American Journal of Infectious Diseases, Vol. 2, Issue 1 · 31 Mar 2006 · 7,314 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation Between Circulating Early Endothelial Progenitors and CD4+CD25+ Regulatory T Cells: A Possible Cross-talk between Immunity and Angiogenesis?Shmuel Schwartzenberg, Adi Mor, Galia Luboshits et al.Regulatory T-cells (Treg) are a recently defined subset of CD4+ cells that can suppress inflammation and induce tolerance. Phenotypically, T-regs are characterized by a high level of expression of the IL-2 receptor alpha chain, CD25. Endothelial progenitor cells (EPCs) can transform into mature endothelial cells and promote vessel formation by inducing postnatal angiogenesis and vasculogenesis. Herein, we tested the hypothesis … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,902 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory Treatment of Infertility in Men with Elevated Antisperm AntibodiesIvan Bubanovic, Slobodan Kojic, Stevo Najman, Zlatibor AndjelkovicPossible causes of subfertility or infertility in men are still poorly defined, but one important category may be elevated level of antisperm antibodies (ASA) caused by infective and/or autoimmune diseases, as well as injuries of male reproductive system. In this study, blood sera from 45 infertile men of different age with ASA positive ELISA test were examined for the serum … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 8,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractPressure-sensitivity Effects on Toughness Measurements of Compact Tension Specimens for Strain-hardening SolidsAbdulhamid A. Al-AbduljabbarThe path-independent J-integral is used as a fracture prediction criterion for loading beyond the elastic limit as Linear Elastic Fracture Mechanics (LEFM) cannot be applied. While J was originally defined from an energy perspective, it was demonstrated that it could be inferred from load-displacement diagrams. Therefore, the Compact Tension (CT) specimen testing is used to compute J for materials. In … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite