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143 results for “Cell model”

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EditorialOpen accessIn the abstractAMYOTROPHIC LATERAL SCLEROSIS: HOW TO UNDERSTAND SUCH DIVERSE AND SO ENTANGLED PHYSIOPATHOLOGY?Carlos Henrique Melo Reis, Marco Orsini, Marco Antônio Araujo Leite et al.When in 1865, JeanMartin Charcotreported patients with progressive muscular atrophysuperimposedwith spasticity of inexorable evolution as result of combinedlesions of the anterior horn and lateral column of the spinal cord, hecertainly inaugurated an attempt on the comprehension of one of the mostcomplexes neurological clinical conditions, which until today persists withimmense voids on their comprehension, regardless of the enormous advancesachieved. Astime went … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Feb 2015 · 7,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractMULTI-STATE MODELS OF HIV/AIDS BY HOMOGENEOUS SEMI-MARKOV PROCESSZelalem Getahun DessieMulti-state stochastic models are useful tools for studying complex dynamics such as chronic diseases. The purpose of this study is to determine factors associated with the progression between different stages of the disease and to model the progression of HIV/AIDS disease of an individual patient under ART follow-up using semi-Markov processes. A sample of 1456 patients has been taken from … …Current Research in Biostatistics, Vol. 4, Issue 2 · 11 Aug 2014 · 8,209 accessesView PDFCite
Research ArticleOpen accessIn the abstractUsing Worldview-2 Satellite Imagery to Support Geoscience Studies on Phlegraean AreaPasquale Maglione, Claudio Parente, Andrea VallarioWorldView-2 satellite imagery includes half-meter panchromatic resolution and 2 m multispectral resolution. Because of the reduced dimensions of pixels and articulated spectral acquisition these images supply detailed information that can be used for geoscience applications, above all to investigate areas, identify land cover, bound vegetated zones, outline transformations (change detection). The aim of this study is to remark possibilities to … …Current Research in Geoscience, Vol. 3, Issue 1 · 4 Sep 2013 · 7,939 accessesView PDFCite
Research ArticleOpen accessIn the abstractDistributed Real Time Architecture for Data Placement in Wireless Sensor NetworksSanjeev Gupta, Mayank DaveProblem statement: Application scenarios of Wireless Sensor Networks (WSN) create interesting design challenges since the sensor nodes used to collect and communicate data may fail suddenly and unpredictably. The issue of real-time and reliable data delivery is extremely important for taking effective decisions in WSN. Approach: In this study we proposed architecture for reliable and real-time approach for data placement … …Journal of Computer Science, Vol. 5, Issue 12 · 31 Dec 2009 · 6,633 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Computer Simulation Model for Automated Quantification of Luteinizing Hormone SecretionAyman Al-Nsour, Hamza A. Ali, Buthynna Al-Dulaimi, Wisam H. Al-SewadiProblem statement: An automated software package is developed for quantifying Luteinizing Hormone (LH) release from pituitary gonadotropes in response to short pulses of Gonadotropin-Releasing Hormone (GnRH). Approach: These computer programs were designed to accommodate the release mechanism that consists of three stages, namely; (1) Production of different concentrations of effectors (such as receptor-hormone binds, G protein interactions, inositol 1,4,5-trisphosphate IP3), … …Journal of Computer Science, Vol. 5, Issue 6 · 30 Jun 2009 · 6,938 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Biomechanical Composite Model to Determine Effective Elastic Moduli of the CNS Gray MatterMehdi Khoshgoftar, Siamak Najarian, Farhad Farmanzad et al.Brain tissue is a heterogeneous material with complicated microstructural features. Models based on microstructure can lead to more accurate and physically realistic predictions of mechanical characteristics of brain tissue. A two-step Mori-Tanaka/Voigt homogenization procedure is implemented into a 3D microstructurally-based multi-phase composite model, composed of randomly-oriented elastic axons, dendrites and neuronal cell bodies surrounded by an elastic matrix. The effects … …American Journal of Applied Sciences, Vol. 4, Issue 11 · 30 Nov 2007 · 7,775 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibitory Effect of Crude Walnut Leaf Polysaccharides on Oxidative Damage of Proteins and Proliferation of SGC-7901 CellsShuqing Yang, Zhike Xie, Shuyan Yu et al.In this paper, we studied the inhibitory effect of crude Walnut Leaf Polysaccharides (WLP) on free radical-induced oxidative damage of proteins and anti-proliferation activity on human Gastric Cancer cells (SGC-7901). The oxidative degradation of Bovine Serum Albumin (BSA), mouse brain proteins (MBP) and Mouse Liver Proteins (MLP) induced by hydroxyl radical and alcoxyl radical was analyzed by Sodium Dodecyl Sulfate-Polyacrylamide … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 26 Apr 2020 · 7,057 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn silico Assessment of the Arg85Trp Glucokinase Mutation EffectsFaiza Bouldjennet, Souhila Bouaziz-Terrachet, Malha Azzouz, Rachida RaacheMaturity Onset Diabetes of the Young (MODY) is a heterogeneous group of autosomal dominantly inherited, young-onset β-cell disorders that account for approximately 2% of non-insulin-dependent diabetics in Europe. MODY2 or GCK-MODY is caused by inactivating heterozygous mutations in the glucokinase. Linkage of MODY to the Arg85Trp GCK mutation, among Algerian diabetic patients has been established in our previous research. The … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,808 accessesView PDFCite
Research ArticleOpen accessIn the abstractTraction Enhancing Products Affect Maximum Torque at the Shoe-Floor Interface: A Potential Increased Risk of ACL InjuryMorse, A., M.M. Mansfield et al.The knee is one of the most frequently injured joints in the body, between 100 000 and 400 000 Anterior Cruciate Ligament (ACL) injuries occur in the United States each year. This investigation explores the impact of wipe- or spray-on sneaker products used to increase traction between shoes and hardwood courts on the loading of the ACL. Specifically, the maximum … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 28 Sep 2016 · 8,327 accessesView PDFCite