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130 articles for “specificity”
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EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,171 accessesView PDFCite
EditorialOpen accessIn the abstractCRISPR-CAS SYSTEM: A FEASIBLE SOLUTION FOR GETTING RID OF PERSISTENT VIRAL INFECTION?Zhaohua ZhongMany viruses, including DNA and RNA viruses, can persistently replicate in the infected cells and cause a prolonged damage. Herpes viruses can be latent in its host cells. Human Immunodeficiency Virus (HIV) reversely transcripts its RNA genome to DNA and integrates to the host’s chromosome. Hepatitis B Virus (HBV) and Human Papilloma Virus (HPV) persistently stay in the host cells … …Current Research in Virology, Vol. 3, Issue 1 · 10 Nov 2014 · 12,620 accessesView PDFCite
Research ArticleOpen accessIn the abstractA FAST AND ACCURATE METHOD FOR AUTOMATIC CORONARY ARTERIAL TREE EXTRACTION IN ANGIOGRAMSRohollah Moosavi Tayebi, Puteri Suhaiza Binti Sulaiman, Rahmita Wirza et al.Coronary arterial tree extraction in angiograms is an essential component of each cardiac image processing system. Once physicians decide to check up coronary arteries from x-ray angiograms, extraction must be done precisely, fast, automatically and including whole arterial tree to help diagnosis or treatment during the cardiac surgical operation. This application is very helpful for the surgeon on deciding the … …Journal of Computer Science, Vol. 10, Issue 10 · 27 Jun 2014 · 8,300 accessesView PDFCite
Research ArticleOpen accessIn the abstractMOLECULAR CHARACTERIZATION AND IMMUNOPROTECTIVE ACTIVITY OF CAPSULAR POLYSACCHARIDE OF KLEBSIELLA PNEUMONIAE ISOLATED FROM FARM ANIMALS AT TAIF GOVERNORATEAhmed M.A. Mansour, Hoda M. Zaki, Nibal A. Hassan, Abdulrahman A. Al-HumianyKlebsiella pneumoniae is a Gram-negative enterobacterium that has historically been and currently remains, a significant cause of human disease and several kinds of infections in animals. In the present work, trials for the isolation of Klebsiella pneumoniae from diseased and apparently healthy farm animals (cows, sheep, goats and camels) were done for recognition of Klebsiella pneumoniae subspecies. It was noticed … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 6 Jan 2014 · 7,942 accessesView PDFCite
Research ArticleOpen accessIn the abstractPERFORMANCE ANALYSIS OF BRAIN TUMOR DIAGNOSIS BASED ON SOFT COMPUTING TECHNIQUESP. Shantha Kumar, P. Ganesh KumarComputed tomography images are widely used in the diagnosis of brain tumor because of its faster processing, avoiding malfunctions and suitability with physician and radiologist. This study proposes a new approach to automated detection of brain tumor. This proposed work consists of various stages in their diagnosis processing such as preprocessing, anisotropic diffusion, feature extraction and classification. The local binary … …American Journal of Applied Sciences, Vol. 11, Issue 2 · 27 Dec 2013 · 6,989 accessesView PDFCite
Research ArticleOpen accessIn the abstractPERFORMANCE ANALYSIS OF GRAY LEVEL CO-OCCURRENCE MATRIX TEXTURE FEATURES FOR GLAUCOMA DIAGNOSISSakthivel Karthikeyan, N. RengarajanGlaucoma is a multifactorial optic neuropathy disease characterized by elevated Intra Ocular Pressure (IOP). As the visual loss caused by the disease is irreversible, early detection is essential. Fundus images are used as input and it is preprocessed using histogram equalization. First order features from histogram and second order features from Gray Level Co-occurrence Matrix (GLCM) are extracted from the … …American Journal of Applied Sciences, Vol. 11, Issue 2 · 24 Dec 2013 · 7,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractA True New Gene: An Invertebrate Antibody Igkappa GeneMichel Leclerc, Nadine Vincent, Magne Osteras, Patricia OttenThe sea star Asterias rubens reacts specifically to the antigen: Horse-Radish Peroxydase (HRP) and produces an «antibody» anti-HRP.We had presented a candidate IgKappa gene corresponding to this last one in 2013. We show now the gene called: «sea star IgKappa gene» in its specificity. We have to know, at the present time that, at our knowledge, the sea star doesn’t … …American Journal of Immunology, Vol. 9, Issue 4 · 24 Sep 2013 · 7,009 accessesView PDFCite
Research ArticleOpen accessIn the abstractTRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES-AMAZING TOOL FOR GENOME EDITINGAvantika Singh, Vivek Pratap SinghTranscription Activator-Like Effector Nucleases (TALENs) are used to cut specific target DNA sequence in order to knock out a gene or to change its sequence. They are formed by the fusion of TALE protein serving as DNA binding domain along with non-specific DNA cleaving nucleases. Its specificity towards DNA bases in the target sequence is derived from the structure of … …OnLine Journal of Biological Sciences, Vol. 13, Issue 3 · 4 Sep 2013 · 8,000 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparison of enzyme Immunoassay with Immunofluorescence Assay for the Diagnosis of Mycoplasma pneumoniae Respiratory Tract Infections in ChildrenOsama Mohammed Saed Abdul-WahabMycoplasma pneumoniae is a frequent cause of acute respiratory infections in both children and adults. Currently, diagnosis of M. pneumoniae infection will based principally on serology and the detection of IgM can provide an early and sensitive diagnosis in children. A variety of commercial immunodiagnostic assays, such as Indirect Enzyme-Linked Immunosorbent (ELISA) assay and Indirect Immunofluorescence (IFA), are now available … …American Journal of Immunology, Vol. 9, Issue 2 · 21 Jun 2013 · 7,416 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Proliferative Diabetic Retinopathy Using Texture SegmentationG. Tamil Pavai, S. Tamil SelviIn this study, it is proposed fast texture segmentation of detection of proliferative diabetic retinopathy. proliferative diabetic retinopathy is characterized by the revascularization on the optic disc or on the retinal area or both, as a result of diabetes mellitus. It may leads to the blindness if it is not detected and treated in proper time. This study proposes a … …Journal of Computer Science, Vol. 9, Issue 3 · 26 Apr 2013 · 6,322 accessesView PDFCite