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126 results for “inhibitory effect”
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Research ArticleOpen accessIn the abstractHighlight of New Phosphodiesterase 10A Inhibitors Using Molecular DockingHalla Belhoula, El Hassen Mokrani, Abderrahmane Bensegueni, Djihane BioudPhosphodiesterase 10A (PDE 10A) is an effective therapeutic approach for treatments of Schizophrenia (SCZ). In order to identify in silico new potent PDE 10A inhibitors, molecular docking approach was used. In this context, the compound S235 was predicted to exhibit a high potential PDE 10A inhibitory activity among 369 compounds tested. The predicted binding energy of this compound was improved … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,701 accessesView PDFCite
Research ArticleOpen accessIn the abstractCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF "NERIUM OLEANDER" LEAVESLakhmili Siham, Obraim Saida, Taourirte Moha et al.The phenolic products of medicinal plants have a great pharmacological interest. This product gives the powers of medicinal plants. They are the source of several active principles widely used in modern medicine. The use of Nerium oleander in Moroccan traditional medicine is very common. Few studies have focused on the chemical analysis and phenolic compounds of this plant. For this, … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 13 Dec 2013 · 8,285 accessesView PDFCite
Research ArticleOpen accessIn the abstractSYNERGY OF A NOVEL ANTIBIOTIC ADJUVANT ENTITY AGAINST MULTI DRUG RESISTANT ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiIn the present investigation, we investigated the in vitro interaction of ceftriaxone plus sulbactam with disodium edetate, a Non Antibiotic Adjuvant (NAA) against selected clinical isolates and in vitro susceptibility studies were also performed. The isolates were tested against a range of ratios of ceftriaxone and sulbactam using a microdilution checkerboard method. Having determined the appropriate ratios of ceftriaxone plus … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 1 Nov 2013 · 7,416 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of Antibodies Against Bovine Herpes Virus 1, Bovine Viral Diarrhea Virus and Bovine Respiratory Syncytial Virus in Early and Ultra-Early Weaned Beef CalvesDiego Daniel Gonzalez, Juan Sebastian Vittone, Martin Lado et al.Bovine respiratory disease is the leading cause of morbidity and mortality in weaned calves. In Argentina, two weaning practices have been implemented. In the early weaning, the calf is removed from the cow at 60-70 days of age while in ultra-early weaning the calf is weaned at 30-45 days of age. The purposes of both systems is to improve cow … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 29 Oct 2013 · 8,384 accessesView PDFCite
Research ArticleOpen accessIn the abstractCOMPARATIVE STUDY OF IN VITRO ANTIMICROBIAL ACTIVITIES OF FOENICULUM VULGARE MILL. (UMBELLIFERAE) EXTRACTKhadija Dahak, Moha TaourirteThe importance to push scientifically the investigations on the organic extracts of the plants aromatic as potential source of new antimicrobial compounds comes from the traditional use of the plants. However, the consumption of these natural products requires à thorough research in this field. The antimicrobial effect of organic and aqueous leaves extracts of Foeniculum vulgare Mill., However, which makes … …OnLine Journal of Biological Sciences, Vol. 13, Issue 4 · 12 Oct 2013 · 8,671 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification and Mode of Action of Antibacterial Components from Melastoma malabathricum Linn LeavesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to assess the antibacterial activity of the methanol extract of Melastoma Malabathricum Leaves (MMML), active fraction of M. Malabathricum Leaves (ML5) and isolated kaempferol-3-O-(2",6"-di-O-p-trans-coumaroyl)-β-glucopyranoside (Kf) and to describe the preliminary mode of action against Gram-positive and Gram-negative bacteria. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) to afford M. malabathricum Leaves fractions (ML1-ML6) of … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 18 Jun 2013 · 12,621 accessesView PDFCite
Research ArticleOpen accessIn the abstractKinetics of Biological Treatment of Low Level Pesticide WastewaterAbdel E. Ghaly, Deepika DavePesticides are chemical substances intended to protect food crops and livestock from pests in order to pro-mote agricultural productivity and protect public health. Contamination of soil, air and water and threat to human and animal health are the major constraints in the use of pesticides. Treatment of pesticide contaminated water is, therefore, paramount. Biological treatment provides the most economical option … …American Journal of Environmental Sciences, Vol. 8, Issue 4 · 4 Jul 2012 · 8,163 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Studies of Lipase from Germinating Oil Seeds (Glycine max)P. P. Gadge, S. D. Madhikar, J. N. Yewle et al.Problem statement: Lipase is one of the important enzymes in food, pharmaceutical, detergent and biofuels industries. Search for the lipase with distinct features, possibly from germinating seeds, is of interest for industrial applications. Approach: The lipase produced by soybean oil seeds was partially purified and characterized in terms of the optimal pH and temperature for activity as well as substrate … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 3 · 19 Jan 2012 · 9,703 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effects of Air Pollution and Smoking on Cadmium Concentration in Human Blood and Correlation with Biochemical ParametersL. Zeneli, H. Paçarizi, N. M. Daci et al.Problem statement: The study described the research of the effects that the environment pollution and smoking have in cadmium concentration in human blood, as well as in the correlation between cadmium and the biochemical parameters. Approach: In a comparative study of cadmium concentration in blood of human population of two different environments in Kosovo, one nearby Kosovo Thermo Power Plants … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 28,194 accessesView PDFCite