95 results for “exert”

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Research ArticleOpen accessIn the abstractNeuroprotection Afforded by GABA Against Oxygen-Glucose Deprivation-Induced Injury in Rat Cortical Brain Slices: An Hormetic Dose-Response EffectLorenzo Ricci, Massimo Valoti, Giampietro Sgaragli, Maria FrosiniThe aim of the present investigation was to assess neuroprotection exerted by GABA (100 nM-100 mM) in rat cortical brain slices subjected to oxygen-glucose deprivation and reoxygenation. Neuronal injury and neuroprotection were assessed by measuring the release of glutamate and lactate dehydrogenase and tissue water content. Results demonstrate that GABA exerted neuroprotective effects according to a U-shaped, hormetic-like, concentration-response curve, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,166 accessesView PDF Cite

Research ArticleOpen accessIn the abstractHormesis and Exercise: How the Cell Copes with Oxidative StressLi Li Ji, Zsolt Radak, Sataro GotoContraction-induced production of reactive oxygen and nitrogen species has been shown to cause oxidative stress to skeletal muscle, heart and other organs. As an adaptive response, muscle antioxidant defense systems are upregulated in response to exercise to restore intracellular prooxidantantioxidant homeostasis. Thus, both young and old animals and humans involved in regular exercise have shown reduced oxidative damage during acute … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,817 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRole of Biopterin Transporter (BT1) Gene on Growth and Infectivity of LeishmaniaManju Jain, Vandana S. Dole, Peter J. Myler et al.Leishmania are known to be auxotrophic for pteridines that are known to play a critical role in the parasites survival. In the present work the role of biopterin transporter in the growth of the parasite and infectivity in to macrophages has been worked out. The role of biopterin transporter in the susceptibility of Leishmania to antimonial compounds has also been … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,038 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAdaptive Control of Robotic Manipulators with Improvement of the Transient Behavior Through an Intelligent Supervision of the Free-Design Parameters and the Sampling PeriodM. De La Sen, A. Almansa, J.C. SotoAn adaptive control scheme for mechanical manipulators proposed. The control loop consists of a network for learning the robot's inverse dynamics and on-line generating the control signal. Some simulation results were provided to evaluate the design. A supervisor was used to improve the performances of the system during the adaptation transients. The supervisor exerts two supervisory actions. The first one … …American Journal of Applied Sciences, Vol. 4, Issue 6 · 30 Jun 2007 · 6,881 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBiochemical and Immunological Study on the Effects of Barley and its Components as Hypoglycemic Agents in Diabetic RatsMokhtar I. Yousef, Medhat Haroun, Mohamed H. El-Masry, Reham EA. AteiaThe present study was carried out to investigate the hypoglycemic effect of barley (Hordeum vulgare L) and some of its components such as amino acids (L-leucine and L-glutamine) and chromium picolinate on some biochemical and immunological parameters of alloxan induced diabetic rats. Alloxan-diabetic rats were treated with barley water (10% w/v) at a dose 10 ml Kg-1 b.wt., chromium picolinate … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 7,233 accessesView PDF Cite