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Research ArticleOpen accessIn the abstractSlow Fungal Hydrolysis of Complex Sugar is Responsible for the Use of Sugar as Vehicle for Antifungal DrugsNedosa Ikenna Valentine, Utoh-Nedosa Uchechukwu Anastasia, Dan Danjuma et al.Problem statement: Aspergillus niger strain (UUF 9202) significantly reduced the dormancy period and boosted aggregate germination time in seeds of Tetrapleura tetraptera by 42% in 32 days and produced a net reduction in mean germination time of the seeds to 12 days. A structure-fungitoxicity relationship study of a series of isoflavonoids against Aspergillus niger and Cladosporium cucumerinum showed that a … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 2 Nov 2011 · 7,666 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproved Application of Paraconsistent Artificial Neural Networks in Diagnosis of Alzheimer's DiseaseHelder F.S. Lopes, Jair M. Abe, Paulo A.M. Kanda et al.Problem statement: The visual analysis of Electroencephalogram (EEG) activity has shown useful as a complementary tool in Alzheimer Disease (AD diagnosis) when the diagnosis remains uncertain, in addition to be used in some clinical protocols. However, this analysis is subject to the inherent equipment imprecision, biological artifact, electrical records, and subjective physician interpretation of the visual analysis variation. The Artificial … …Neuroscience International, Vol. 2, Issue 1 · 6 Oct 2011 · 12,068 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of Extended-Spectrum β Lactamases and AmpC β-Lactamase Production in Escherichia coli Causing Urinary Tract Infection among HIV and Non-HIV PatientsPadmavathy Kesavaram, Padma Krishnan, Rajasekaran SikhamaniProblem statement: Opportunistic infections have been documented as a leading cause of morbidity among HIV patients. Gram negative pathogens that elaborate beta-lactamases have been reported to be associated with increased morbidity and mortality, especially amongst immunocompromised patients on intensive care and high-dependency units. The most common mechanism of β-lactam drug resistance in Escherichia coli include ESBL, AmpC production. Approach: In … …Current Research in Medicine, Vol. 2, Issue 1 · 18 Aug 2011 · 7,837 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Rumen Acid Load on Postpartum Performance and Blood Metabolic Responses in Transition Holstein CowsSadjad Danesh Mesgaran, Alireza Vakili, Alireza Heravi Moosavi, Ghasem KoolabadiProblem statement: The transition period is the most stressful time in the production cycle of a dairy cow because of depressed feed intake, endocrine and metabolic changes at parturition. The aim was to determine the effect of rumen acid load on postpartum performance and metabolic parameters in transition Holstein cows. Approach: The Acidogenicity Values (AV) of the diets were determined … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 25 May 2011 · 7,444 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of a Prophylactic Dose of Ibuprofen on Plasma Level of Interleukin 1, Interleukin 6 and Tumor Necrosis Factor-Alpha in a 1500 m Running PracticeGholamreza Sepehri, Mohammad Pourranjbar, Ghollam-Reza Moshtaghi-Kashanian et al.Problem statement: there are controversies about the effects of anti-inflammatory drugs on exercised induced changes on plasma cytokines in untrained male athletes, so the primary purpose of this study was to measure the influence of a prophylactic dose of ibuprofen use on plasma cytokines during a 1500 m running race. Approach: Subjects were 10 untrained male Medical University students who … …American Journal of Applied Sciences, Vol. 8, Issue 1 · 31 Jan 2011 · 7,892 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiscrete Wavelet Transform Based Classification of Human Emotions Using Electroencephalogram SignalsMohamed RizonProblem statement: The aim of this study was to report the human emotion assessment using Electroencephalogram (EEG). Approach: An audio-visual induction based protocol was designed for inducing five different emotions (happy, surprise, fear, disgust and neutral) on 20 subjects in the age group of 19~39 years. EEG signals are recorded from 64 channels placed over entire scalp according to International … …American Journal of Applied Sciences, Vol. 7, Issue 7 · 31 Jul 2010 · 7,554 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling the Distribution of Rainfall Intensity using Hourly DataSalisu Dan'azumi, Supiah Shamsudin, Azmi ArisProblem statement: Design of storm water best management practices to control runoff and water pollution can be achieved if a prior knowledge of the distribution of rainfall characteristics is known. Rainfall intensity, particularly in tropical climate, plays a major role in the design of runoff conveyance and erosion control systems. This study is aimed to explore the statistical distribution of … …American Journal of Environmental Sciences, Vol. 6, Issue 3 · 30 Jun 2010 · 9,006 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Heterogeneity in Phase II Clinical TrialsChristopher N. Barnes, Shesh N. RaiProblem statement: The common assumption in non-randomized Phase II clinical trials is a homogeneous population with homogeneous response. This assumption is at odds with many trials today; a heterogeneous response due to the existence of subgroups. Approach: In order to examine the effects of heterogeneity on the trial outcome, a systematic platform is developed to quantify the range and classes … …Current Research in Biostatistics, Vol. 1, Issue 1 · 30 Jun 2010 · 10,131 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtraction of Essential Oil from Nigella sativa Using Supercritical Carbon Dioxide: Study of Antibacterial ActivityNagi A. Alhaj, Mariana N. Shamsudin, Hana F. Zamri, Rasedee AbdullahThe antimicrobial activity of N. sativa essential oil obtained by supercritical fluid extraction by carbon dioxide was investigated against Gram Positive and Gram negative strains, isolated from clinical specimens. Best conditions for Black cumin oil extraction are obtained at 400 bar, 40°C and a solvent flow rate of 25 g min-1. The seed extracts were prepared by supercritical fluid extraction … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 4 · 31 Dec 2008 · 8,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractProteomics Approach for Investigating the Disease Resistance Using Cucumber as Model PlantSaligrama A. Deepak, Junko Shibato, Hideo Ishii et al.The profile of proteins induced in cucumber leaves pretreated with Acibenzolar-S-Methyl (ASM) and challenge inoculated with Colletotrichum orbiculare are presented. ASM was applied to the first leaf and the third leaf collected at different time intervals of 0-48 h and the total protein extracted using trichloroacetic acid acetone was analyzed by two-dimensional gel electrophoresis. Increased expressions of pyridoxine biosynthesis protein, … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,243 accessesView PDFCite