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106 articles for “Therapeutic Effects”

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Research ArticleOpen accessIn the abstractPreliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendensTriana Hertiani, Ediati Sasmito, Sumardi, Maria UlfahProblem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 13,403 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Acute Administration of Artemisia Persia Extracts on Arterial Blood Pressure and Heart Rate in RatsFarzaneh Esmaeili, Gholamreza Sepehri, Ghollam-Reza Moshtaghi-Kashanian et al.Problem statement: Artemisia Persia (AP) used for its therapeutic effects in folk medicine whiles some species of Artemisia shown a hypotensive effect. To determine the cardiovascular effect of AP, we tested the pharmacological responses of aqueous and methanolic extracts of AP on blood pressure (BP) and Heart Rate (HR) of normotensive and ephedrine induced hypertensive rats using a tail-cuff computerized … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 7,659 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Antidiabetic Efficacy of Combined Extracts from Two Continental Plants: Azadirachta indica (A. Juss) (Neem) and Vernonia amygdalina (Del.) (African Bitter Leaf)Patrick Ekong Ebong, Item Justin Atangwho, Eyong Ubana Eyong, Godwin Eneji EgbungPolyherbal therapy is said to be a current pharmacological principle having the advantage of producing maximum therapeutic efficacy with minimum side effects. We assessed the antidiabetic efficacy and hence the impact on biochemical indices of toxicity by a combination of extracts from neem and bitterleaf. Thirty rats, 25 diabetic and 5 non-diabetic rats, were used for the study. The diabetic … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 31 Aug 2008 · 14,404 accessesView PDFCite
Research ArticleOpen accessIn the abstractCurcuma longa, Glycyrrhiza glabra and Moringa oleifera Ameliorate Diclofenac-induced Hepatoxicity in RatsAlaaeldin A. HamzaAlthough treatment with therapeutic agents may be one of the main causes of liver toxicity, there have been only limited attempts at thorough research efforts to seek solution. Diclofenac (DIC) is a widely used anti-inflammatory drug that causes liver toxicity. This DIC-induced hepatotoxicity was found to be associated with oxidative damage. In this report, extracts of herbal plants that are … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 9,618 accessesView PDFCite
Research ArticleOpen accessIn the abstractAqueous Extract of Inonotus bliquus (Fr.) Pilat (Hymenochaetaceae) Significantly Inhibits the Growth of Sarcoma 180 by Inducing ApoptosisCaifa Chen, Weifa Zheng, Xiaowen Gao et al.Inonotus obliquus (Fr.) Pilat (Hymenochaetaceae) has been widely used as a folk medicine to treat various cancers in Russia, Poland and most of Baltic countries for literally more than four centuries. However, in spite of its therapeutic significance for cancers, this fungus has not been studied systematically for the mechanisms of antitumor activity. In this study, we report the effects … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 1 · 31 Mar 2007 · 21,115 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntranasal Administration of Quercetin Liposome Decreases Anxiety-like Behavior and Increases Spatial MemoryJintanaporn Wattanathorn, Wathita Phachonpai, Aroonsri Priprem, Saengrawee SuthiparinyanontAt present, the effects of quercetin liposome on anxiolytic activity and cognitive function are unclearly known. In this study, male Wistar rats were administered quercetin liposome via intranasal route once daily continually for 4 weeks. The anxiolytic activity and cognitive enhancing effect were determined after single administration, 1, 2, 3 and 4 weeks of treatment using elevated plus maze test … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 1 · 31 Mar 2007 · 9,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractHeroin-Induces Differential Protein Expression by Normal Human Astrocytes (NHA)Jessica L. Reynolds, Supriya D. Mahajan, Donald Sykes, Madhavan P.N. NairHeroin use is postulated to act as a cofactor in the neuropathogenesis of human immunodeficiency virus (HIV-1) infection. Astrocytes, integral components of the CNS, are reported to be susceptible to HIV-1 infection. Upon activation, astrocytes release a number of immunoregulatory products or modulate the expression of a number of proteins that foster the immunopathogenesis of HIV-1 infection. However, the role … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,267 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory Treatment of Infertility in Men with Elevated Antisperm AntibodiesIvan Bubanovic, Slobodan Kojic, Stevo Najman, Zlatibor AndjelkovicPossible causes of subfertility or infertility in men are still poorly defined, but one important category may be elevated level of antisperm antibodies (ASA) caused by infective and/or autoimmune diseases, as well as injuries of male reproductive system. In this study, blood sera from 45 infertile men of different age with ASA positive ELISA test were examined for the serum … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 8,842 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordTherapeutic Potential of Medicinal Plants Grown in the Bundelkhand Region of India for Addressing Severe Non-communicable DiseasesNeelam Kashyap, Abha Sachan, Prakash Chandra et al.Herbal Medicines (HMs) have experienced exponential development in the past few years. Consequently, their natural origins and minimal side effects, the popularity of these medications is gradually growing across the globe. Ancient text Rigveda has well documented the remedial application of medicinal herbs for the management of a spectrum of disorders. Phytometabolites derived from plants are rich in bioactive agents, … …American Journal of Agricultural and Biological Sciences, Vol. 20, Issue 1 · 17 Jun 2025 · 6,958 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordEffects of Mulberry Fruit Powder in Animal Model of StrokePratchaya Kaewkaen, Terdthai Tong-Un, Jintanaporn Wattanathorn et al.Stroke is the leading cause of death and the important cause of disability worldwide. Presently, the effectiveness of therapeutic strategy is still very limited. Based on the role neuroprotective effect of substance possessing antioxidant effect previously reported, we hypothesized mulberry fruit a substance possessing anti-oxidant activity, might be able to protect against cognitive impairment induced by stroke or cerebral ischemia. … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 15 Aug 2012 · 9,042 accessesView PDFCite