7 results for “Yuqing Zhang”

Research ArticleOpen accessIn the author namesOptimization of Preparation Procedures of Phlorizin-Zn (Ⅱ) Complex and Its Antioxidant Activity Study in vitroYuqing Zhang, Yaping Li, Guorui Yang et al.Flavonoid metal complexes possess more effective antioxidant properties than flavonoids. However, the preparation of the phlorizin-Zn (Ⅱ) complex and its antioxidant activity has not been reported. In this research, the preparation procedures of the phlorizin-Zn (Ⅱ) complex were enhanced using by single factor test and Response Surface Methodology (RSM). The optimal preparation procedures of the phlorizin-Zn (II) complex were as … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 3 Apr 2024 · 4,758 accessesView PDF Cite

Research ArticleOpen accessIn the author namesThe Effect of Trilobatin on Bovine Serum Albumin: Interaction Mechanism and Molecular DockingYuhan Zhai, Yuqing Zhang, Yaping Li et al.Understanding the transport and distribution of small molecules in vivo is aided by studying their interactions with proteins. As a natural sweetener, trilobatin possesses several biological activities. However, uncertainty surrounds the trilobatin and Bovine Serum Albumin (BSA) interaction mechanism. In this study, the binding types, number of binding sites and binding constants of trilobatin interaction with BSA were studied by … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 29 Mar 2024 · 4,843 accessesView PDF Cite

Research ArticleOpen accessIn the author namesTrilobatin Possesses Protective Potentials on H2O2-Induced HepG2 Cells by Suppressing Oxidative Stress: Involvement of Nrf2/Keap1 Signal PathwayYuhan Zhai, Yuqing Zhang, Yaping Li et al.Trilobatin, a natural dihydrochalcone compound, possesses various biological activities. However, few investigations have been carried out on the mechanisms of trilobatin against oxidative stress. To comprehend the effects and mechanism of trilobatin on oxidative stress after hepatic injury, H2O2-induced HepG2 cells were used in this research. The results indicated that trilobatin enhanced the viability and improved the apoptosis morphology of … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 22 Dec 2023 · 5,087 accessesView PDF Cite

Research ArticleOpen accessIn the author namesAntioxidant Activity of Trilobatin and Its Inhibitory Effects on Oxidative Damage of Biological MacromoleculesYuhan Zhai, Yuqing Zhang, Yaping Li et al.Excessive levels of free radicals in the body cause oxidative damage to macromolecules by injuring DNA, proteins, and lipids, which leads to structural and functional defects and ultimately results in a number of illnesses. The antioxidation of trilobatin and its inhibitory activity of trilobatin on oxidative damage of biological macromolecules have not been thoroughly investigated. In this research, the effects … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 28 Oct 2023 · 5,466 accessesView PDF Cite

Research ArticleOpen accessIn the author namesPreparation of Low-Sugar Herbal Buccal Tablet and its Antioxidant ActivityYuqing Wang, Mingjie Sun, Rui Xu et al.In this study, in order to prepare a low-sugar Herbal Buccal Tablet (HBT), Response Surface Methodology (RSM) was used to optimize the formula of HBT. HBT was prepared by wet granulation and tableting process on the basis of formula optimization. The in vitro antioxidant activity, glycemic index and particle microstructure of HBT were evaluated. The results showed that the optimal … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 8 Mar 2022 · 6,357 accessesView PDF Cite

Research ArticleOpen accessIn the author namesPreparation of Rosemary Collagen Chitosan Blend Membrane Using Response Surface Methodology (RSM)Ming He, Yuhan Zhai, Yuqing Zhang et al.The present research provided a formula for the optimization of rosemary/collagen/chitosan blend membrane. Rosemary Extract (RE) was used as additive and membrane was prepared using tensile strength, elongation at break and elongation length as the indexes. The results of single factor experiment showed that the addition ratio of collagen to chitosan, additive content, glycerol content and drying temperature all affected … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 22 Nov 2021 · 6,239 accessesView PDF Cite