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11 results for “Yan Chen”

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Research ArticleOpen accessIn the author namesUPLC-Q-Exactive Orbitrap-MS Analysis of Anchusa italica Retz. Flowers: Molecular Docking, Dynamics Modeling, and Pharmacokinetics for Cardiovascular DiseaseLinyang Wang, Yan Chen, Ainiwaer Aikemu, Shuge TianThis study builds on prior UPLC-Q-Exactive Orbit rap-MS analyses of Anchusa italica Retz. Flowers (Airfs) to explore their anti-cardiovascular mechanis·ms and key bioactive markers. UPLC-Q-Exactive Orbitrap-MS identified 30 major compounds, including polyphenols and flavonoids with strong antioxidant activity. The potential active ingredients were then screened using Lipinski's rule of five, and a network pharmacology method was employed to construct an … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Oct 2025 · 2,601 accessesView PDFCite
Research ArticleOpen accessIn the author namesKnowledge, Training Status and Willingness to Implement Cardiopulmonary Resuscitation of Medical University Students in Chongqing, ChinaHuixian Zhou, Chuan Pu, Feng Chen et al.Timely bystander Cardiopulmonary Resuscitation (CPR) is key to improving survival from out-of-hospital cardiac arrest. Medical university students are potential bystander CPR providers. This study aimed to identify the current level of CPR knowledge, the present status of training and factors affecting the willingness to perform CPR among medical university students in Chongqing, China. Random sampling method was used and a … …Journal of Social Sciences, Vol. 17, Issue 1 · 5 Apr 2021 · 7,609 accessesView PDFCite
Research ArticleOpen accessIn the author namesAcer Buergerianumas a New Resource for the Extraction of Corilagin: Determination of Corilaginin Different Cultivars of A. Buergerianumby UPLCQian Qiao, Chong Wu, Jiangyong Wang et al.Corilagin is a promising anticancer drug candidate. Acer nikoense and A. ammonium are both known to contain corilagin. To explore whether corilagin occurs in congeneric species and to fully develop the medicinal value of maple, the corilagin content in different varieties of maple was determined by Ultrahigh-Performance Liquid Chromatography (UPLC). Acer buergerianum leaves contained corilagin and the corilagin content in … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 12 May 2022 · 5,710 accessesView PDFCite
Research ArticleOpen accessIn the author namesComparative Analysis of UGT1A9 Genetic Polymorphisms between Chinese Han and Tibetan PopulationsWei Yan, Jian Cui, Yuewen Wang et al.Although various polymorphisms have been identified in the UGT1A9 gene in the main sorts of ethnic groups in the world, no investigations have been focused on the Chinese Tibetan populations and the comparison between Chinese Tibetan and Han populations to date. This study was designed to systematically compare genetic differences between the two populations. We investigated the functional regions of … …Current Research in Medicine, Vol. 3, Issue 2 · 23 Aug 2012 · 7,647 accessesView PDFCite
Research ArticleOpen accessIn the author namesFoxp3-Mediated Immunity of Human Pancreatic Cancer Cell Line PANC-1Renxi Wang, Gencheng Han, Jianan Wang et al.Problem statement: More and more evidences have shown that human cancer cells can express Foxp3, the regulatory T cell-associated transcription factor. The role of Foxp3 in human cancer cells is still unclear. We detected Foxp3 expression in human pancreatic cancer cell line PANC-1. SiRNA assays showed that Foxp3 expression suppressed the expression of TGF-β and IL-10 which could induce immune … …American Journal of Immunology, Vol. 5, Issue 4 · 11 Jan 2010 · 7,367 accessesView PDFCite
Research ArticleOpen accessIn the author namesExtraction, Partial Identification and Bioactivities of Total Flavonoids from Carex meyeriana KunthHongbiao Wang, Penghui Wang, Xiudong Yang et al.To date, knowledge associated with extraction, chemical constituents and bioactivities of Total Flavonoids from Carex meyeriana Kunth (TFCMK) that remains unclear. Therefore, this paper was designed to optimize the ethanol reflux extraction method by response surface methodology and determine the chemical constituents by Liquid Phase-Mass Spectrometry (HPLC-MS); additionally, the bioactivities including antioxidant, antibacterial and hemolysis test were also explored. The … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 7 Aug 2019 · 7,525 accessesView PDFCite
Research ArticleOpen accessIn the author namesOptimization of Cellulase-Assisted Extraction of Total Flavonoids from Corn Bract and Evaluation of Antioxidant and Antibacterial AactivitiesYang Zhang, Jing Lu, Leijie Ben et al.Corn bract is a corn-based agricultural waste material that distributed worldwide. In present work, response surface methodology was applied to optimize the cellulase-assisted extraction of Total Flavonoids from Corn Bract (TFCB), the in vitro antioxidant and antibacterial as well as the in vivo antioxidant activities of TFCB were investigated. Results showed that the optimal conditions for TFCB extraction were as … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 2 · 18 May 2019 · 8,505 accessesView PDFCite
Research ArticleOpen accessIn the author namesAn Entire-Array-Polygon (EAP) Method to Assess Urban Development SuitabilityLong Cheng, Yan LiuChina has been experiencing rapid urbanization since the economic reforms and open-up in the late 1970s, with the expansion and restructuring of existing cities taking place at an unprecedented pace, as well as the emergence of many new cities. However, it remains a challenge for urban planners and decision-makers to identify and assess the suitability of areas for future urban … …American Journal of Environmental Sciences, Vol. 12, Issue 4 · 2 Jul 2016 · 7,682 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,949 accessesView PDFCite