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6 results for “T. C. Okoye”
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Research ArticleOpen accessIn the author namesSTUDIES ON GASTROINTESTINAL EFFECTS OF DESMODIUM VELUTINUM: A TRADITIONAL REMEDY FOR DIARRHEAA. C. Ezike, P. A. Akah, C. O. Okoli et al.The gastrointestinal and antibacterial properties of dichloromethane: Methanol extract (DVE) and fractions (DVHF, DVDF and DVMF) from Desmodium velutinum Willd. DC. (Fabaceae) leaves were investigated. The extract and fractions significantly (p 5g kg-1 in mice. Results demonstrated that D. velutinum leaf possesses gastrointestinal antimotility and antispasmodic effects and mild antibacterial and gastroprotective activities. …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 12 Mar 2014 · 7,953 accessesView PDFCite
Research ArticleOpen accessIn the author namesEvaluation of the Toxic Effects of Dihydroartemisinin on the Vital Organs of Wistar Albino RatsA. U. Utoh-Nedosa, P. A. Akah, T. C. Okoye, C. O. OkoliProblem statement: The current surge in the use of Artemisinin based Combination Therapy (ACT) in the treatment of falciparium resistant malaria in the tropics and the potentials of Dihydroartemisinin (DHA), a member of the artemisinin family, to produce toxic effect in the vital organs (such as the liver, heart, lungs, intestine, spleen kidney and blood cells) necessitated this research. Approach: … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 9,187 accessesView PDFCite
Research ArticleOpen accessIn the author namesStudies on Wound Healing and Antiulcer Activities of Extract of Aerial Parts of Phyllanthus niruri L. (Euphorbiaceae)C. O. Okoli, A. C. Ezike, P. A. Akah et al.Problem statement: Phyllanthus niruri is widely used in many parts of the world to manage a wide range of diseases. As part of efforts to elucidate its pharmacological activities and hence medicinal potential, we studied the wound healing and antiulcer properties of extract of the aerial parts using experimentally-created wounds and ulcers in rodents. Approach: Wound healing effect was assessed … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 10,094 accessesView PDFCite