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6 results for “Nagi A. ALHaj”

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Research ArticleOpen accessIn the author namesCharacterization of Nigella Sativa L. Essential Oil-Loaded Solid Lipid NanoparticlesNagi A. ALHaj, Mariana N. Shamsudin, Norfarrah M. Alipiah et al.Problem statement: Seeds of Nigella Sativa L., commonly known as black seed, have been used in traditional medicine by many Asian, Middle Eastern and Far Eastern Countries to treat headache, coughs, abdominal pain, diarrhea, asthma, rheumatism and other diseases. The seeds of this plant are the most extensively studied, both phytochemically and pharmacologically. The aqueous and oil extracts of the … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 17,874 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe Effects of Recombinant Human Erythropoietin and Tamoxifen on Growth and Angiogenesis of Mammary Tumor in Sprague-Dawley RatA. K. Sairah, A. Rasedee, O. Sheikh et al.Problem statement: Erythropoietin receptor (EPOR) has been detected in breast cancer cells and speculated to be involved in cancer growth, viability and angiogenesis. This has risen suspicious that EPO administration may enhance the severity of cancer. Approach: This study was undertaken to determine the effects of rHuEPO, Tamoxifen and their combination on the growth and angiogenesis of mammary tumor. Female … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 7,804 accessesView PDFCite
Research ArticleOpen accessIn the author namesExtraction of Essential Oil from Nigella sativa Using Supercritical Carbon Dioxide: Study of Antibacterial ActivityNagi A. Alhaj, Mariana N. Shamsudin, Hana F. Zamri, Rasedee AbdullahThe antimicrobial activity of N. sativa essential oil obtained by supercritical fluid extraction by carbon dioxide was investigated against Gram Positive and Gram negative strains, isolated from clinical specimens. Best conditions for Black cumin oil extraction are obtained at 400 bar, 40°C and a solvent flow rate of 25 g min-1. The seed extracts were prepared by supercritical fluid extraction … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 4 · 31 Dec 2008 · 8,205 accessesView PDFCite
Research ArticleOpen accessIn the author namesTamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization TechniquesNagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim, Ahmad BustamamAs drug delivery systems Nanoparticulate widely investigated because of many advantages such as smaller size, controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity. So, Solid Lipid Nanoparticles have recently received considerable attention as alternative drug delivery carrier. In this study Solid Lipid Nanoparticles (SLNs) containing tamoxifen, nonsteroidal antiestrogens have been loaded and to be … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 15,168 accessesView PDFCite