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4 results for “Manju Jain”

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Research ArticleOpen accessIn the author namesHepatitis B and C Positivity in Various Categories of Human Immunodeficiency Virus Seropositive Individuals in a Regional STD Centre-an Eight-Year Evaluation of Trends and Risk FactorsSumathi Muralidhar, Manju Bala, Rakesh Kumar Jain et al.Problem statement: Among the various infections whose incidence has increased since the advent of HIV/AIDS, Hepatitis B and C stand out clearly. This is so because the routes of transmission of these infections are essentially the same as those of HIV/AIDS, making co-infections a common occurrence. The risk of infection for Hepatitis B and C is several times more than … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,926 accessesView PDFCite
Research ArticleOpen accessIn the author namesCreation of Tetracycline Regulatable Knockouts of ORFF Gene from the LD1 Locus of Leishmania donovaniBindu Sukumaran, Manju Jain, Peter J. Myler et al.The tetracycline repressor/operator system was adapted for use in Leishmania donovani. In order to investigate the possible importance and function of open reading frame F (ORFF) in Leishmania donovani strain AG83 that has a single copy of ORFF in the LD1 locus on chromosome 35, we have attempted to generate tetracycline regulatable single allele mutants of ORFF. Leishmania cells expressing … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,832 accessesView PDFCite
Research ArticleOpen accessIn the author namesRole of Biopterin Transporter (BT1) Gene on Growth and Infectivity of LeishmaniaManju Jain, Vandana S. Dole, Peter J. Myler et al.Leishmania are known to be auxotrophic for pteridines that are known to play a critical role in the parasites survival. In the present work the role of biopterin transporter in the growth of the parasite and infectivity in to macrophages has been worked out. The role of biopterin transporter in the susceptibility of Leishmania to antimonial compounds has also been … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,040 accessesView PDFCite