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28 results for “M. K. Gautam”
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Research ArticleOpen accessIn the author namesRandom Forest and Extreme Gradient Boosting with Bayesian Hyperparameter Optimization for Landslide Susceptibility Mapping in Penang Island, MalaysiaDorothy Anak Martin Atok, Soo See Chai, Kok Luong Goh et al.Landslide susceptibility models often face challenges of overfitting and overestimation. This research focuses on improving the predictive capabilities of the Extreme Gradient Boosting (XGBoost) and Random Forest (RF) algorithms by applying Bayesian Hyperparameter Optimization (BayesOpt). Penang Island, a region in Malaysia prone to frequent landslides, was chosen as the study area. Ten Landslide Conditioning Factors (LCFs), including elevation, slope angle, … …Journal of Computer Science, Vol. 21, Issue 10 · 16 Dec 2025 · 3,103 accessesView PDFCite
Research ArticleOpen accessIn the author namesEmerging Trends in Designing Short and Efficient Protein Purification ProtocolsSaurabh Gautam, Joyeeta Mukherjee, Ipsita Roy, Munishwar Nath GuptaProtein purification is carried out in both academic and industrial sectors. Both non-chromatographic approaches (precipitation, crystallization, partitioning) and chromatographic methods are used. When recombinant proteins are over expressed in foreign hosts, inclusion bodies are obtained. Many purification methods can be used to refold proteins. Many strategies allow one to avoid formation of inclusion bodies. The concept of affinity based separation … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 4 · 25 Dec 2012 · 9,007 accessesView PDFCite