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Case ReportOpen accessIn the author namesBrief Report: 20-Year Follow-Up of an Infant with Neurological Impairment Born to a Mother with Variant Creutzfeldt-Jakob DiseaseJustin Penner, Anjali Rampersad, James E. Burns et al.A term infant born via uncomplicated caesarian section was noted to be jittery, hypotonic, and have pooling of secretions at birth. Over the first four weeks of life, the infant developed four limb hypertonia, hyperreflexia, and clonus. MRI at 3.5 weeks old showed brain immaturity, poor myelination, and increased signal in the dorsal thalami. At six months, dystonic features with … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 7 Mar 2025 · 7,666 accessesView PDFCite