4 results for “David E. Anderson”

Research ArticleOpen accessIn the author namesAntibody Responses to HIV-1 gp120 Hypervariable Regions in Six Long-Term Non-ProgressorsRebecca Rivera, Kyung Hee Kang, Murray B. Gardner et al.Our long-term goal is to discover the combination of host parameters that help some HIV-infected individuals to resist progression to AIDS. In this study, we examined antibody responses using multiple samples obtained from a cohort of Long-Term Non-Progressors (LTNPs). Our hypothesis is that antibody responses to variable regions of the HIV-1 envelope glycoprotein are involved in reducing the viral load … …American Journal of Infectious Diseases, Vol. 12, Issue 2 · 1 Jul 2016 · 7,658 accessesView PDF Cite

Research ArticleOpen accessIn the author namesAnamnestic Immune Response Eight Years After Immunization of Primates with a Multivalent HIV-1 GP120 Variable Peptide VaccineRebecca Rivera, Kyung Hee Kang, David E. Anderson et al.Successful development of an effective HIV vaccine hasn’t occurred yet partly as a consequence of the antigenic variation deployed by HIV-1 to escape the immune system. Our laboratory is dedicated to develop a single peptide synthesis approach to create multivalent peptides representing hypervariable epitopes of the gp120 envelope glycoprotein of HIV-1. Our previous study showed that our HIV HECs are … …American Journal of Immunology, Vol. 9, Issue 1 · 13 Mar 2013 · 7,212 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordExistence and Uniqueness Conditions for the Maximum Likelihood Solution In Regression Models For Correlated Bernoulli Random VariablesDavid Todem, KyungMann KimWe give sufficient and necessary conditions for the existence of the maximum likelihood estimate in a class of multivariate regression models for correlated Bernoulli random variables. The models use the concept of threshold crossing technique of an underlying multivariate latent variable with univariate components formulated as a linear regression model. However, in place of their Gaussian assumptions, any specified distribution … …Journal of Mathematics and Statistics, Vol. 3, Issue 3 · 30 Sep 2007 · 6,844 accessesView PDF Cite