The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain: A Literature Review
Racha Hajj1 & Camille Haddad1 Show affiliations
- Saint-Joseph University, Lebanon
Current Research in Dentistry, Volume 12, Issue 1, pp. 62–70 · doi.org/10.3844/crdsp.2021.62.70
Abstract
The aim of this article is to describe the new actions of botulinum toxin A for chronic pain treatment. BT/A inhibits the exocytosis of synaptic vesicles containing the pain mediators neurotransmitters, reduces the post traumatic trigeminal neuralgia pain, inhibits the release of microglia derived TNF-α as well as other pro inflammatory cytokines, viable treatment option in the case of patients who do not respond to conservative treatment methods of chronic pain (medication) BT/A is an emerging treatment for chronic pain; patients with severe chronic facial pain, not responding to conventional treatments, can respond to botulinum type a injections
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Hajj, R. & Haddad, C. (2021). The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain: A Literature Review. Current Research in Dentistry, 12(1), 62–70. https://doi.org/10.3844/crdsp.2021.62.70
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