Microtia After Ovulation Induction with Letrozole

Problem statement: Letrozole gained lots of interest over the past decayed as a medication for ovulation induction to achieve monofollicular results, although few retrospective analysis of congenital anolamalies detected for babies who were conceived via this medication; the dispute still exist and the need for large multicenter studies are needed to resolve this issue. Approach: In the current report; we report a case of microtia who was conceived as a result of ovulation induction with letrozole. Results: This case draws our attention to the safety of letrozole as an ovulation induction medication. Conclusion: The reported case here mandates that babies delivered as a consequence of ovulation induction with aromatase inhibitors should be examined antenatal and postnatally for possible congenital anomalies and to be reported to settle the argument weather theses medications are safe or not in term of ovulation induction.