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Research Article · Open access · Published 7 January 2015

Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals

Livia Maria Gonçalves Rossi1 & Paula Rahal1

American Journal of Infectious Diseases, Volume 10, Issue 4, pp. 179–183 · doi.org/10.3844/ajidsp.2014.179.183

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Abstract

Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.

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Gonçalves Rossi, L. M. & Rahal, P. (2014). Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals. American Journal of Infectious Diseases, 10(4), 179–183. https://doi.org/10.3844/ajidsp.2014.179.183

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Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting AntiviralsAmerican Journal of Infectious Diseases · Volume 10, Issue 4 · pp. 179–183 · CC BY 3.0Download