Volume 1, Issue 2 (2010) | Current Research in Medicine

Determination of Iron Deficiency among Human Immunodeficiency Virus Sero Positives

M. A. Pradeep — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.77.79

Problem statement: Iron is an important dietary mineral and involves in various body functions. In humans, iron is an essential component of proteins involved in oxygen transport. It is also essential...

A Study on Erythrocytic Determination of Anemic Condition among Human Immunodeficiency Virus Sero Positives

M. Andrew Pradeep — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.80.83

Problem statement: Acquired Immuno Deficiency Syndrome (AIDS) is growing health hazard throughout the world. In developing countries like India anemia is highly prevalent in the population due to the ...

Role of Hematological and Alternate Markers in Human Immunodeficiency Virus Disease Progression

K. V. Ramana — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.84.87

Problem statement: The knowledge of HIV infection has expanded tremendously which has led to significant improvement in the treatment, leading to decrease in morbidity and mortality. Considering the l...

Formulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery System

C. D. Licy — 2010-10-30

Current Research in Medicine, Published online: 30 October 2010; doi:10.3844/amjsp.2010.88.96

Problem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldw...

The Effects of Protease Inhibitors on Metabolic Complications and Lipodystrophy in Human Immunodeficiency Virus-Infected Patients

Mohd Khaza — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.97.102

Problem statement: Highly Active Antiretroviral Therapy (HAART)-associated metabolic complications include lipoatrophy (loss of Subcutaneous Adipose Tissue (SAT) and insulin resistance. The risk of Di...

Hepatitis B and C Positivity in Various Categories of Human Immunodeficiency Virus Seropositive Individuals in a Regional STD Centre-an Eight-Year Evaluation of Trends and Risk Factors

Sumathi Muralidhar — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.103.108

Problem statement: Among the various infections whose incidence has increased since the advent of HIV/AIDS, Hepatitis B and C stand out clearly. This is so because the routes of transmission of these ...

Zinc Deficiency and Associated T-Cell Dysfunctioning among Human Immunodeficiency Virus Seropositives

M. Andrew Pradeep — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.109.112

Problem statement: All the nutrients in the diet play a crucial role in maintaining an optimal immune response. In both, deficient and excessive intake of nutrients can have negative consequence on th...

A Cross-sectional Study of Sexual Practices, Sexually Transmitted Infections and Human Immunodeficiency Virus among Male-to-Female Transgender People

P.S. Saravanamurthy — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.113.119

Problem statement: Designing HIV interventions requires evidence on links between behaviors and elevated transmission risk that remains scanty for male-to-female Transgender (TG) people in India. Appr...

First Report of Human Immunodeficiency Virus Type 1 Circulating Recombinant Form 02_AG Recombinant Strain of African Origin from North India

Ujjwal Neogi — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.120.125

Problem statement: Human Immunodeficiency Virus Type-1 (HIV-1) displays extensive genetic diversity globally which poses a serious challenge in making efficacious vaccine and developing effective ther...

Analysis of Resistance to Human Immunodeficiency Virus Protease Inhibitors Using Molecular Mechanics and Machine Learning Strategies

A. Harishchander — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.126.132

Problem statement: Drug resistance is the most important factor, which influences the failure of current HIV therapies. So, the ability to predict the drug resistance of HIV-1 protease mutants will be...

Human Immunodeficiency Virus and Carcinoma Cervix

A. Jaisri — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.133.135

Problem statement: Carcinoma of the cervix is the second leading cause of death in women in the world. Human Papilloma Virus (HPV) which plays a major role in the etiology of cervical cancer is said t...

To Seek the Hidden Monster

K. K. Rahul — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.136.139

Problem statement: The asymptomatic stage of HIV infection is dealt with in detail in all Dermatology books. Patients in this stage present with skin lesions that occur even in the immunocompetent. Ho...

Frequency of P/S(XX)P Duplication and FRFE, Absence of LYP in P6Gag of Indian Human Immunodeficiency Virus-1 Subtype C Isolates

Krutika Wadekar — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.140.147

Problem statement: The presence of a p6 domain at the C-terminus of the Gag polyprotein is a characteristic feature of HIV-1 and other primate lentiviruses. The p6Gag protein is considered as a major ...

Comparative Docking Analysis on Natural Compounds Versus a Synthetic Drug as a Therapeutic for Acquired Immuno Deficiency Syndrome

Sandhya R. Nair — 2010-10-31

Current Research in Medicine, Published online: 31 October 2010; doi:10.3844/amjsp.2010.148.150

Problem statement: Acquired Immune Deficiency Syndrome (AIDS) is one of the worst pandemics affecting and spreading quickly all over the world with a high mortality rate. AIDS has been able to kill so...

Identification of Novel Human Immunodeficiency Virus-1 Integrase Inhibitors by Shape-Based Virtual Screening

T.K. Omprakash — 2010-12-31

Current Research in Medicine, Published online: 31 December 2010; doi:10.3844/amjsp.2010.151.156

Problem statement: Human Immunodeficiency Virus-1 (HIV-1) is causative agent of the immune system disease, Acquired Immune Deficiency Syndrome (AIDS). Majority of anti-HIV drugs target reverse transcr...

Evaluation of Nested PCRs targeting the BI and SAG2 Genes For Detection of Toxoplasma gondii Genome in Aqueous Humor From HIV Positive Toxoplasma Retinochoroiditis Patients in a Tertiary Eye Hospital

B. Mahalakshmi — 2010-12-31

Current Research in Medicine, Published online: 31 December 2010; doi:10.3844/amjsp.2010.157.163

Abstract: Problem statement: To evaluate nPCR targeting B1 gene (primer set 1) with 3 other nPCRs targeting B1 gene (primer set 2), 3' end of SAG2 and 5' end of SAG2 gene, for detection of Toxoplasma ...