Volume 2, Issue 1 (2011) | Current Research in Biostatistics

A Bayesian Method for Disentangling Dependent Structure of Epistatic Interaction

Jing Zhang — 2012-01-13

Current Research in Biostatistics, Published online: 13 January 2012; doi:10.3844/amjbsp.2011.1.10

Problem statement: We propose a Bayesian method (RBP) to recursively infer the independence structure of epistatic interactions in case-control study. Approach: Based on the results of BEAM2, RBP can ...

Measures of Explained Variation and the Base-Rate Problem for Logistic Regression

Dinesh Sharma — 2012-02-25

Current Research in Biostatistics, Published online: 25 February 2012; doi:10.3844/amjbsp.2011.11.19

Problem statement: Logistic regression, perhaps the most frequently used regression model after the General Linear Model (GLM), is extensively used in the field of medical science to analyze prognosti...

Truncated Estimate in Log-Binomial Model: Algorithm and Simulation

Luyan Dai — 2012-05-07

Current Research in Biostatistics, Published online: 7 May 2012; doi:10.3844/amjbsp.2011.20.25

Problem statement: Relative risk has concrete meanings of comparing two groups and measuring the association between exposures and outcomes in medical and public health studies. Log-binomial model, us...